Drugs / sodium fluoride
sodium fluoride
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | COLGATE TOTAL | — | 1997-07-11 | fda.gov ↗ |
Trials 69 · started per year
today
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 03 trials | ||||||
| Phase 0 | NCT06708481 | Aug 2024 → Feb 2025 overdue | — | October 6 University | Recruiting | No outcome recorded |
| Phase 0 | NCT04620252 | Feb 2021 → Mar 2022 | dental caries | University of Michigan | Completed | No outcome recorded |
| Phase 0 | NCT02486458 | Apr → Dec 2015 | dental caries | University of Campinas, Brazil | Completed | No outcome recorded |
| Phase 17 trials | ||||||
| Phase 1 | NCT06316323 | Feb → Sep 2023 | dental caries | Universiti Teknologi Mara | Completed | No outcome recorded |
| Phase 1 | NCT04239872 | Mar 2020 → Apr 2021 | — | University of Michigan | Completed | Mixed |
| Phase 1 | NCT03285360 | Oct 2017 → Dec 2018 | dentin sensitivity | Cairo University | Completed | No outcome recorded |
| Phase 1 | NCT03434782 | Apr → Nov 2017 | dentin sensitivity | Federal University of Pará | Completed | No outcome recorded |
| Phase 1 | NCT03044171 | Aug 2016 → Jan 2017 | dentin sensitivity | Federal University of Pará | Completed | No outcome recorded |
| Phase 1 | NCT02645617 | Mar → Sep 2016 | dental caries | Advantage Dental Services, LLC | Completed | No outcome recorded |
| Phase 1 | NCT01589458 | Aug 2011 → Feb 2012 | dental caries | University of Campinas, Brazil | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT02877888 | Aug 2016 → Oct 2018 | dental caries | University of Peradeniya | Completed | No outcome recorded |
| Phase 29 trials · 4 met primary | ||||||
| Phase 2 | NCT07371117 | Nov 2025 → Feb 2026 | dental caries | University of Jazan | Completed | No outcome recorded |
| Phase 2 | NCT06932926 | Sep 2025 → Mar 2026 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT06892834 | Mar → Jun 2025 | gingivitis | Procter and Gamble | Completed | No outcome recorded |
| Phase 2 | NCT06174012 | Dec 2023 → Nov 2024 overdue | — | Sun Yat-sen University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT03238352 | Aug → Oct 2017 | dentin sensitivity | GlaxoSmithKline | Completed | Met primary |
| Phase 2 | NCT04183231 | Nov 2016 → Feb 2017 | dental caries | Advantage Silver Dental Arrest, LLC | Completed | No outcome recorded |
| Phase 2 | NCT02207400 | Aug 2014 → Feb 2015 | — | GlaxoSmithKline | Completed | Met primary |
| Phase 2 | NCT02207907 | Aug 2014 → Feb 2015 | — | GlaxoSmithKline | Completed | Met primary |
| Phase 2 | NCT01128972 | Aug → Oct 2009 | tooth disorder | GlaxoSmithKline | Completed | Met primary |
| Phase 2/31 trial | ||||||
| Phase 2/3 | NCT02128633 | Nov 2009 → Jun 2013 | dentin sensitivity | Federal University of Santa Maria | Completed | No outcome recorded |
| Phase 316 trials · 7 met primary · 4 missed | ||||||
| Phase 3 | NCT07398846 | Jan → Apr 2026 | — | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT06048627 | Mar → Oct 2024 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT06010732 | Oct 2023 → Feb 2024 | dental caries | Indiana University | Completed | Missed primary |
| Phase 3 | NCT05761041 | Mar 2022 → Mar 2023 | dental caries | Alexandria University | Completed | Missed primary |
| Phase 3 | NCT03383783 | Dec 2017 → May 2018 | dental caries | Domenick Zero | Completed | No outcome recorded |
| Phase 3 | NCT03296072 | Nov 2017 → Jan 2018 | tooth erosion, non-bacterial | GlaxoSmithKline | Completed | Met primary |
| Phase 3 | NCT02019160 | Sep 2014 → Jun 2018 | dental caries | The University of Hong Kong | Completed | Met primary |
| Phase 3 | NCT02341352 | Apr 2013 → Apr 2015 | dental caries | Zhejiang University | Unknown | No outcome recorded |
| Phase 3 | NCT01641237 | Mar → May 2012 | tooth erosion, non-bacterial | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 3 | NCT01607411 | Feb → May 2012 | dental caries | GlaxoSmithKline | Completed | Met primary |
| Phase 3 | NCT03191721 | Jun 2010 → Dec 2014 | periodontitis | University of Guarulhos | Completed | Met primary |
| Phase 3 | NCT01005966 | Nov 2008 → Mar 2009 | dental caries | GlaxoSmithKline | Completed | Missed primary |
| Phase 3 | NCT00708305 | Jun → Oct 2008 | dental caries | GlaxoSmithKline | Completed | Missed primary |
| Phase 3 | NCT00708123 | Nov 2007 → Apr 2008 | dental caries | GlaxoSmithKline | Completed | Met primary |
| Phase 3 | NCT00758394 | Sep → Nov 2007 | — | Colgate Palmolive | Completed | Met primary |
| Phase 3 | NCT00435500 | Jun 2003 → Jan 2006 | dental caries | University of Toronto | Unknown | Met primary |
| Phase 411 trials · 2 met primary · 1 missed | ||||||
| Phase 4 | NCT07829328 | Sep 2026 → Feb 2027 expected | smooth surface dental caries | Tripler Army Medical Center | Enrolling by invitation | No outcome recorded |
| Phase 4 | NCT07807397 | Sep 2026 → Sep 2027 expected | dental caries, gingivitis | Colgate Palmolive | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06172764 | Dec 2023 → Oct 2025 overdue | enamel caries | Dow University of Health Sciences | Recruiting | No outcome recorded |
| Phase 4 | NCT06051981 | Oct 2023 → Feb 2024 | — | Riyadh Elm University | Unknown | No outcome recorded |
| Phase 4 | NCT05772039 | Jan 2022 → Jul 2023 | dentin caries | Universiti Sains Malaysia | Unknown | No outcome recorded |
| Phase 4 | NCT04887389 | Aug 2021 → Sep 2022 | dental caries | Nisreen Ibrahim khan | Completed | No outcome recorded |
| Phase 4 | NCT04050722 | Oct → Nov 2019 | gingivitis | GlaxoSmithKline | Completed | Met primary |
| Phase 4 | NCT02424097 | May 2013 → Oct 2016 | smooth surface dental caries | University of California, San Francisco | Completed | No outcome recorded |
| Phase 4 | NCT01128946 | Nov 2009 → Mar 2010 | dental caries | GlaxoSmithKline | Completed | No outcome recorded |
| Phase 4 | NCT01563172 | Jan → Jun 2009 | dental caries | GlaxoSmithKline | Completed | Met primary |
| Phase 4 | NCT00723515 | Feb → Jun 2007 | dental caries | University of Pernambuco | Completed | Missed primary |
| Phase not applicable21 trials · 5 met primary · 1 missed | ||||||
| — | NCT07352956 | Jan → Apr 2026 | dentin sensitivity | HALEON | Completed | No outcome recorded |
| — | NCT07141576 | Sep 2025 → Jul 2026 overdue | dentin sensitivity | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06896565 | Jun → Aug 2025 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06949072 | Apr → Sep 2025 | dental caries | HALEON | Completed | No outcome recorded |
| — | NCT06829277 | Nov 2024 → Jan 2025 | dentin sensitivity | MTI University | Completed | No outcome recorded |
| — | NCT07419737 | Oct → Dec 2024 | smooth surface dental caries | Church & Dwight Company, Inc. | Completed | No outcome recorded |
| — | NCT07425509 | Sep → Nov 2024 | — | Church & Dwight Company, Inc. | Completed | No outcome recorded |
| — | NCT07229105 | Aug 2024 → Mar 2025 | dental caries, leukoplakia, tooth resorption | Bezmialem Vakif University | Completed | No outcome recorded |
| — | NCT05969756 | Jul 2023 → Oct 2024 | pit and fissure surface dental caries | Hue University of Medicine and Pharmacy | Completed | No outcome recorded |
| — | NCT05654662 | Feb → Nov 2023 | gingivitis, smooth surface dental caries | HALEON | Completed | Met primary |
| — | NCT04788550 | Mar 2021 → Sep 2022 | malposition of teeth with or without hypodontia/oligodontia | University of Malaya | Unknown | Missed primary |
| — | NCT07153328 | Jan 2021 → Mar 2024 | dental caries | Beaty Dent | Completed | No outcome recorded |
| — | NCT06749977 | Jan 2020 → Jan 2021 | — | Medical University of Sofia | Completed | No outcome recorded |
| — | NCT05588518 | Apr 2019 → Feb 2020 | dentin sensitivity | King Khalid University | Completed | No outcome recorded |
| — | NCT03360266 | Mar → Dec 2016 | dental caries | Indira Gandhi Institute of Dental Science | Completed | No outcome recorded |
| — | NCT02399163 | Apr → Jul 2015 | dental caries | GlaxoSmithKline | Completed | Met primary |
| — | NCT03571815 | Jan 2015 → Dec 2016 | dental caries | University of Peradeniya | Completed | No outcome recorded |
| — | NCT02221349 | Aug → Oct 2014 | dentin sensitivity | Procter and Gamble | Completed | No outcome recorded |
| — | NCT02195583 | Jun → Aug 2014 | — | GlaxoSmithKline | Completed | Met primary |
| — | NCT01665911 | Aug 2012 → Apr 2013 | dental caries | Frank Lippert | Completed | Met primary |
| — | NCT01657903 | Nov 2011 → Feb 2012 | tooth erosion, non-bacterial | GlaxoSmithKline | Completed | Met primary |
| Comparator or background therapy64 trials | ||||||
| Phase 0 | NCT06566833 Comparator | Aug 2023 → Oct 2024 | — | Alexandria University | Completed | No outcome recorded |
| Phase 0 | NCT03089567 Comparator | Sep 2017 → Jan 2018 | dental caries | Yale University | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 1 | NCT07027566 Comparator | Jul 2025 → May 2026 overdue | dentin sensitivity | Federal University of Pará | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT06358066 Comparator | Jun → Nov 2024 | — | Tanta University | Unknown | No outcome recorded |
| Phase 1 | NCT06182267 Background | Nov → Dec 2023 | dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 2 | NCT07455604 Comparator | Jan 2026 → Aug 2028 expected | dental caries | The University of Hong Kong | Active not recruiting | No outcome recorded |
| Phase 2 | NCT05272254 Background | Sep 2022 → May 2027 expected | dental caries | University of Rochester | Active not recruiting | No outcome recorded |
| Phase 2 | NCT04947527 Comparator | Jun 2022 → Jun 2024 | dental caries | Advantage Silver Dental Arrest, LLC | Completed | Mixed |
| Phase 2 | NCT04750902 Comparator | Jan 2021 → Feb 2024 | dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 2 | NCT03082196 Comparator | Mar 2017 → May 2019 | dental caries | Advantage Dental Services, LLC | Completed | Mixed |
| Phase 2 | NCT03323372 Comparator | Dec 2016 → May 2017 | dentin sensitivity | Federal University of Amazonas | Completed | No outcome recorded |
| Phase 2 | NCT02598778 Comparator | Nov 2015 → Apr 2016 | dental caries | Montefiore Medical Center | Terminated | No outcome recorded Stop: Enrollment |
| Phase 2 | NCT02226562 Background | Sep → Dec 2014 | dentin sensitivity | GlaxoSmithKline | Completed | Met primary |
| Phase 2 | NCT01831817 Comparator | Jan → May 2013 | dentin sensitivity | GlaxoSmithKline | Completed | Missed primary |
| Phase 2 | NCT01691560 Comparator | Aug → Nov 2012 | dentin sensitivity | GlaxoSmithKline | Completed | Mixed |
| Phase 2 | NCT00752089 Comparator | Sep 2007 → Jan 2008 | tooth erosion, non-bacterial | GlaxoSmithKline | Completed | Met primary |
| Phase 2/3 | NCT04484844 Comparator | Oct → Dec 2020 | dentin sensitivity | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT04422860 Comparator | Oct 2020 → Sep 2021 | dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT04485299 Comparator | Oct → Dec 2020 | dentin sensitivity, hypersensitivity reaction disease | Cairo University | Unknown | No outcome recorded |
| Phase 2/3 | NCT05084001 Comparator | Mar 2020 → Jul 2023 | pit and fissure surface dental caries | The University of Hong Kong | Unknown | No outcome recorded |
| Phase 2/3 | NCT04804423 Comparator | Jan 2020 → Mar 2021 | dental caries, dentin sensitivity | University Medicine Greifswald | Completed | No outcome recorded |
| Phase 3 | NCT07849270 Comparator | Aug 2026 → Jan 2027 expected | dental caries, tooth erosion, non-bacterial | Indiana University | Active not recruiting | No outcome recorded |
| Phase 3 | NCT07398378 Comparator | Jun → Jul 2026 overdue | mouth disorder | Colgate Palmolive | Active not recruiting | No outcome recorded |
| Phase 3 | NCT07263698 Comparator | Dec 2025 → Feb 2026 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT07478640 Comparator | Apr 2024 → Jun 2025 | dentin sensitivity | Federal University of Pará | Completed | No outcome recorded |
| Phase 3 | NCT06180707 Comparator | Jan → Mar 2024 | dentin sensitivity | Federal University of Pará | Unknown | No outcome recorded |
| Phase 3 | NCT06770114 Comparator | Oct 2021 → May 2022 | gingivitis | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT04249336 Comparator | Sep 2019 → Jan 2021 | dentin sensitivity | Dow University of Health Sciences | Completed | No outcome recorded |
| Phase 3 | NCT05560945 Comparator | Apr 2019 → Mar 2022 | dental caries | Colgate Palmolive | Completed | No outcome recorded |
| Phase 3 | NCT03546491 Comparator | May → Jun 2018 | — | Procter and Gamble | Completed | No outcome recorded |
| Phase 3 | NCT03423797 Comparator | Sep 2017 → May 2020 | dental caries | The University of Hong Kong | Completed | Met primary |
| Phase 3 | NCT02829879 Comparator | Dec 2015 → Sep 2016 | dentin sensitivity | University of Chile | Unknown | No outcome recorded |
| Phase 3 | NCT00759187 Comparator | Jan → Apr 2008 | gingival disorder | Colgate Palmolive | Completed | No outcome recorded |
| Phase 4 | NCT07814898 Comparator | Feb → May 2026 | gingivitis | University of Science and Technology, Yemen | Completed | No outcome recorded |
| Phase 4 | NCT06608368 Background | Oct → Nov 2024 | dentin sensitivity | HALEON | Completed | No outcome recorded |
| Phase 4 | NCT03557996 Comparator | Dec 2018 → Nov 2019 | dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT03554980 Comparator | Dec 2018 → Nov 2019 | dental caries | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT02936830 Comparator | Oct 2016 → Mar 2017 | dentin sensitivity | Riyadh Colleges of Dentistry and Pharmacy | Completed | No outcome recorded |
| Phase 4 | NCT02319668 Background | Feb → Jun 2015 | — | GlaxoSmithKline | Completed | Missed primary |
| Phase 4 | NCT07211061 Comparator | Sep → Nov 2011 | gingivitis | Procter and Gamble | Completed | No outcome recorded |
| Phase 4 | NCT02935322 Comparator | Sep 2009 → Dec 2011 | dental caries, periodontal disorder | University of Oslo | Completed | No outcome recorded |
| — | NCT07839780 Comparator | Oct 2026 → Dec 2027 expected | smooth surface dental caries | National University of Malaysia | Not yet recruiting | No outcome recorded |
| — | NCT07711132 Comparator | Dec 2025 → Dec 2026 expected | enamel caries | Mansoura University | Recruiting | No outcome recorded |
| — | NCT07273539 Comparator | Oct 2025 → Feb 2026 | gingivitis | HALEON | Completed | No outcome recorded |
| — | NCT07181967 Comparator | Sep → Dec 2025 overdue | dental caries | Assiut University | Recruiting | No outcome recorded |
| — | NCT07056855 Comparator | Jul 2025 overdue | dentin sensitivity | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07419763 Comparator | Apr → Jun 2025 | dental caries | Church & Dwight Company, Inc. | Completed | No outcome recorded |
| — | NCT07640399 Comparator | Mar → Jun 2025 | gingivitis | Church & Dwight Company, Inc. | Completed | No outcome recorded |
| — | NCT06660069 Comparator | Nov 2024 → Mar 2025 | gingivitis, smooth surface dental caries | HALEON | Completed | Met primary |
| — | NCT06837779 Comparator | Jul 2024 → Aug 2025 overdue | dentin sensitivity | Al-Azhar University | Enrolling by invitation | No outcome recorded |
| — | NCT06131957 Background | Jan 2024 → Jan 2027 expected | root caries | The University of Hong Kong | Active not recruiting | No outcome recorded |
| — | NCT06143670 Comparator | Nov 2023 → Mar 2024 | gingivitis | HALEON | Completed | Met primary |
| — | NCT05750745 Comparator | May → Sep 2023 | dentin sensitivity | HALEON | Completed | Missed primary |
| — | NCT05064137 Comparator | Mar → Dec 2022 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT06013735 Comparator | Feb 2020 → Jun 2021 | gingival disorder | Suez Canal University | Completed | No outcome recorded |
| — | NCT04124887 Comparator | Feb 2017 → Feb 2018 | tooth resorption | Kırıkkale University | Completed | No outcome recorded |
| — | NCT03625310 Comparator | Nov 2016 → Jul 2017 | dental caries | Merve Erkmen Almaz | Completed | No outcome recorded |
| — | NCT02574221 Comparator | Aug → Oct 2015 | gingivitis | Procter and Gamble | Completed | No outcome recorded |
| — | NCT02543060 Comparator | Jun → Aug 2015 | gingivitis | Procter and Gamble | Completed | No outcome recorded |
| — | NCT01549587 Comparator | Feb 2012 → Feb 2014 | gingivitis, pregnancy disorder | Procter and Gamble | Completed | No outcome recorded |
| — | NCT01345292 Comparator | Apr → May 2011 | dentin sensitivity | Johnson & Johnson Consumer and Personal Products Worldwide | Completed | No outcome recorded |
| — | NCT01009554 Comparator | Oct → Dec 2009 | — | Johnson & Johnson Consumer and Personal Products Worldwide | Completed | No outcome recorded |
| — | NCT00612469 Comparator | Oct 2005 → Jul 2006 | dental caries | Federal University of Ceará | Completed | No outcome recorded |
| — | NCT00497029 Background | Jun 2004 → Aug 2006 | dental caries | University of Maryland, Baltimore | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 137 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | sodium fluoride | “OBJECTIVE: To measure the effectiveness of fluoride varnish (FV) (Duraflor), 5% sodium fluoride, Pharmascience Inc., Montréal, QC, Canada) and caregiver counseling in...” PMID 18422711 ↗ Apr 2008133“OBJECTIVES: To compare three children's sodium fluoride toothpastes to placebo with respect to enamel remineralisation potential, enamel fluoride uptake and net acid resistance...” PMID 24283282 ↗ Dec 2013 “The goal of this 36-month double-blind randomized controlled trial is to compare the effects of 5% sodium fluoride varnish (22,600 ppm fluoride) with or without Strontium-doped...” NCT06131957 ↗ “The students meeting the inclusion and exclusion criteria was randomly assigned, using block randomization in blocks of four, using a computer generated set of random numbers,...” NCT02877888 ↗ “In previous studies, povidone iodine (PVP-I), a widely used bactericidal antiseptic, and sodium fluoride (NaF), used to foster remineralization of enamel, were applied...” PMID 30938600 ↗ Apr 2018 “A chewable candy chewed for 30 seconds, immediately followed by a 1 minute rinse with an over the counter sodium fluoride mouthwash, at a concentration of 0.05% (226 parts per...” NCT04620252 ↗ “Children in group A received a semiannual application of a 25% silver nitrate (AgNO3) solution followed by a commercially available varnish with 5% sodium fluoride (NaF) on the...” PMID 32866050 ↗ Aug 2020 “The investigation assessed the clinical effect of a mouthrinse containing chlorhexidine (CHX) and sodium fluoride (NaF) during a 4-day period of non-brushing and a 6-week...” NCT02935322 ↗ “FV (Duraflor®- 5% Sodium Fluoride Varnish, Bubble gum flavor, AMD Medicom, Inc. Quebec, Canada) that is the standard of care will be applied with the manufacturer's supplied applicator.” NCT05272254 ↗ “Sodium fluoride, at a concentration of 0.05% (226 parts per million (ppm) of fluoride), will be used to rinse the mouth for 1 minute and expectorated.” NCT04239872 ↗ “Dental brushing with a toothpaste containing 0.3% triclosan and 1450 ppm sodium fluoride in a regular maintenance program for 24 months.” NCT03191721 ↗ |
| Known as | Charm varnish | “five percent sodium fluoride varnish (Charm varnish -Dentkist- Korea).” NCT06932926 ↗ |
| Known as | Charm varnish R | “5% sodium fluoride (22.600ppm) Dentkist-korea Charm varnish R” NCT06358066 ↗ |
| Known as | Colgate Cavity Protection | “Participants will brush their teeth with Colgate Cavity Protection repair and protect (containing sodium fluoride)” NCT04050722 ↗ |
| Known as | Duraflor | “OBJECTIVE: To measure the effectiveness of fluoride varnish (FV) (Duraflor), 5% sodium fluoride, Pharmascience Inc., Montréal, QC, Canada) and caregiver counseling in...” PMID 18422711 ↗ Apr 20081“FV (Duraflor®- 5% Sodium Fluoride Varnish, Bubble gum flavor, AMD Medicom, Inc. Quebec, Canada) that is the standard of care will be applied with the manufacturer's supplied applicator.” NCT05272254 ↗ |
| Known as | Duraphat | “5% NaF varnish (Duraphat, Colgate Palmolive, USA)” NCT05084001 ↗ |
| Known as | fluoride varnish 22600ppm | “intervention: drug :fluoride varnish 22600ppm topical application every 6 months for a total period of 2 years” NCT02877888 ↗ |
| Known as | NaF | “The aim of this trial is to investigate the effectiveness of semiannual application of 38% SDF and that of 5% sodium fluoride (NaF) varnish when compared with placebo control...” PMID 35604758 ↗ May 202219“In previous studies, povidone iodine (PVP-I), a widely used bactericidal antiseptic, and sodium fluoride (NaF), used to foster remineralization of enamel, were applied...” PMID 30938600 ↗ Apr 2018 “Considering the widespread use of sodium fluoride (NaF) and monofluorophosphate (MFP) based toothpastes, the present study aim to evaluate F availability in saliva after use of...” NCT01589458 ↗ “Children in group A received a semiannual application of a 25% silver nitrate (AgNO3) solution followed by a commercially available varnish with 5% sodium fluoride (NaF) on the...” PMID 32866050 ↗ Aug 2020 “The investigation assessed the clinical effect of a mouthrinse containing chlorhexidine (CHX) and sodium fluoride (NaF) during a 4-day period of non-brushing and a 6-week...” NCT02935322 ↗ “A possible affordable alternative may be Sodium Fluoride (NaF) varnish combined with good oral hygiene promoted by parental Motivational Interviewing (MI).” PMID 37789300 ↗ Oct 2023 “Arrestment proportion of caries for sodium fluoride varnish was found to be 84.4% (NaF) and 85.3% for ( NaF + chlorohexidine mouth wash) .” NCT03554980 ↗ “Crest Cavity Protection Fresh Lime is containing 1150 parts per million (ppm) fluoride as Sodium fluoride (NaF).” NCT05750745 ↗ “Topical application of varnish fluoride (sodium fluoride NaF) effect on exposed dentine as a desensitizing agent” NCT04484844 ↗ “The Fluoride varnish (containing 5% NaF, Duraphat®, Colgate-Palmolive Company, NY, USA)” NCT06131957 ↗ “Sodium Fluoride with Casein Phosphopeptide-Amorphous Calcium Phosphate (NaF + CPP-ACP)” NCT07371117 ↗ |
| Known as | sodium fluoride (PCCA Sodium Fluoride USP 51927-1038-00) | “sodium fluoride (PCCA Sodium Fluoride USP 51927-1038-00)” NCT01665911 ↗ |
| Route | Topical | “professionally applied topical fluoride (PATF) applications at regular intervals” NCT00435500 ↗ |