drugset / Trial / NCT05761041

Silver Diamine Fluoride Versus Sodium Fluoride Varnish With Parental Behavior Modification in Arresting Early Childhood Caries

NCT05761041

RandomizedParallel-groupDouble-blindPrevention

Summary

Arresting dental caries using silver diamine fluoride (SDF) has gained attention recently for the management of early childhood caries (ECC). However, black staining is one of its drawbacks. A possible affordable alternative can be Sodium Fluoride (NaF) supported with good oral hygiene induced by parental Motivational Interviewing (MI). The trial aims to compare the impact of SDF versus NaF supported by MI on lesion activity in preschool children.

Timeline

Start
2022-03-28
Primary completion
2023-03-30
Completion
2023-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator silver diammine fluoride Small molecule 38 %
Subject sodium fluoride Unknown 5 %

Indications