drugset / Trial / NCT05761041
Silver Diamine Fluoride Versus Sodium Fluoride Varnish With Parental Behavior Modification in Arresting Early Childhood Caries
Phase 3
Completed
140 enrolled
Alexandria University
Science,Technology & Innovation Funding Authority, Egypt · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
Arresting dental caries using silver diamine fluoride (SDF) has gained attention recently for the management of early childhood caries (ECC). However, black staining is one of its drawbacks. A possible affordable alternative can be Sodium Fluoride (NaF) supported with good oral hygiene induced by parental Motivational Interviewing (MI). The trial aims to compare the impact of SDF versus NaF supported by MI on lesion activity in preschool children.
Timeline
- Start
- 2022-03-28
- Primary completion
- 2023-03-30
- Completion
- 2023-04-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | silver diammine fluoride | Small molecule | 38 % | — |
| Subject | sodium fluoride | Unknown | 5 % | — |