A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks

Summary

The aim of this study is to investigate the impact of a stannous fluoride containing toothpaste in reducing gingivitis when used twice daily for a maximum for 3 weeks, when compared to a standard sodium fluoride toothpaste (negative control).

Timeline

Start

2019-10-07

Primary completion

2019-11-13

Completion

2019-11-13

Outcome

Met primary endpoint

registry analysis (superiority test); Sensodyne Repair and Protect (Test Dentifrice) vs Colgate Cavity Protection (Negative Control Dentifrice); p <0.0001; Adjusted Mean Difference -0.06 NCT04050722 ↗

Publications

• Acherkouk A, Patel N, Butler A, Amini P. A randomised clinical study investigating efficacy of a stannous fluoride toothpaste in improving gingival health after 3 weeks' use. BMC Oral Health. 2021 Sep 12;21(1):441. doi: 10.1186/s12903-021-01727-5.

Drugs

Indications