drugset / Trial / NCT01657903

Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion

NCT01657903

Completed 56 enrolled GlaxoSmithKline
RandomizedCrossoverSingle-blindTreatment

Summary

The purpose of this study is to compare and evaluate the ability of two European Union (EU) regulated gel to foam toothpaste formulations versus a non-fluoride toothpaste using a modified in-situ model of dental erosion and remineralization. A positive control i.e fluoride containing toothpaste marketed in EU will also be compared to non-fluoride toothpaste.

Timeline

Start
2011-11
Primary completion
2012-02
Completion
2012-02

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium fluoride Unknown 1450 ppm Topical
Background Potassium Nitrate Other / unclassified 5 % Topical