drugset / Trial / NCT07425509
Evaluation of a Stannous Fluoride Dentifrice for Control of Oral Malodor
RandomizedCrossoverTriple-blindTreatment
Summary
This single-center, randomized, double-blind, two-treatment crossover clinical study evaluated the safety and efficacy of a stannous fluoride-containing dentifrice compared with a sodium fluoride control dentifrice for the control of intrinsic oral malodor. Adult subjects brushed twice daily with each product during separate treatment periods following standardized wash-out periods. Oral malodor was assessed using trained organoleptic judges applying a validated Odor Intensity (OI) scale at baseline and multiple post-treatment time points.
Timeline
- Start
- 2024-09-09
- Primary completion
- 2024-11-04
- Completion
- 2024-11-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium fluoride | Unknown | 0.243 % | Oral |
| Subject | stannous fluoride | Small molecule | 0.454 % | Oral |
Indications
No indication recorded.