drugset / Trial / NCT02598778

Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction

NCT02598778

Phase 2 Terminated 12 enrolled Montefiore Medical Center
RandomizedParallel-groupOpen-labelBasic science

Summary

This study compared four mouth rinses/chews for their ability to reduce Streptococcus Mutans after usage. The four that were compared were chlorhexidine gluconate (0.12%), sodium fluoride (0.05%), paraffin wax chewing gum (sugar free), and deionized water. The paraffin wax chewing gum replaced the originally planned coconut oil and served as a placebo comparator.

Timeline

Start
2015-11-01
Primary completion
2016-04-01
Completion
2016-04-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Chlorhexidine gluconate Other / unclassified 0.12 % Oral
Comparator Chlorhexidine gluconate Other / unclassified 10 ml Oral
Comparator sodium fluoride Unknown 0.05 % Oral
Comparator sodium fluoride Unknown 10 ml Oral

Indications