P11-4 and Fluoride Varnish for Remineralization of Post-orthodontic Lesions

Summary

This clinical study aims to compare the remineralizing effects of self-assembling peptide P11-4 (SAP11-4) with fluoride varnish in the treatment of post-orthodontic non-cavitated carious lesions (NCLs). The study uses the QLF camera to assess changes in lesion size, severity, and mineralization, evaluating the effectiveness of SAP11-4 in comparison to fluoride varnish or no treatment. The primary endpoint is the change in QLF parameters, alongside ICDAS scores and Nyvad criteria for clinical evaluation.

Timeline

Start

2020-01-01

Primary completion

2021-01-01

Completion

2023-02-20

Drugs

Indications

No indication recorded.