drugset / Trial / NCT05750745
A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to evaluate the efficacy of the 0.454 percentage (%) weight/weight (w/w) stannous fluoride (SnF2) toothpastes for the relief of dentine hypersensitivity (DH) in China.
Timeline
- Start
- 2023-05-08
- Primary completion
- 2023-09-19
- Completion
- 2023-09-19
Outcome
Missed primary endpoint
registry analysis (superiority test); Test Dentifrice (Sensodyne Sensitivity and Gum) vs Negative Control (Crest Cavity Protection Fresh Lime); p = 0.0871; Adjusted Mean Difference -0.17 (95% CI -0.36 to 0.02); Mixed Model with Repeated Measure (MMRM) NCT05750745 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | PHOSPHINE SILANE | Other / unclassified | 5 % | Topical |
| Comparator | sodium fluoride | Unknown | 1150 ppm | Topical |
| Subject | stannous fluoride | Small molecule | 0.454 % | Topical |