drugset / Trial / NCT06949072
A Clinical Study to Assess an Experimental Dentifrice in an Experimental Model of Early Stage Caries
RandomizedCrossoverSingle-blindTreatment
Summary
The aim of this study is to evaluate the relative efficacy of an experimental dentifrice containing 1150 parts per million (ppm) fluoride (as sodium fluoride \[NaF\]) to remineralize early stage caries type lesions in an in situ model compared to a negative control and a reference dentifrice.
Timeline
- Start
- 2025-04-28
- Primary completion
- 2025-09-11
- Completion
- 2025-09-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Potassium Nitrate | Other / unclassified | 5 % | — |
| Subject | sodium fluoride | Unknown | 1150 ppm | — |
| Subject | stannous fluoride | Small molecule | 1100 ppm | — |