drugset / Trial / NCT01128946

Enamel Remineralization Potential of Dentifrices in Situ

NCT01128946 ↗

Phase 4 Completed 83 enrolled GlaxoSmithKline
RandomizedCrossoverDouble-blindPrevention

Summary

This study will use an oral in-situ caries model to study remineralization of enamel due to the action of different combinations of fluoride salts delivered from dentifrices.

Timeline

Start
2009-11
Primary completion
2010-03
Completion
2010-03

Drugs

EvaluationDrugModalityDoseRoute
Subject NaMFP Unknown 1000 ppm —
Subject sodium fluoride Unknown 350 ppm —
Subject sodium fluoride Unknown 450 ppm —
Subject sodium fluoride Unknown 675 ppm —
Subject sodium fluoride Unknown 1450 ppm —
Subject stannous fluoride Small molecule 1100 ppm —

Indications