drugset / Trial / NCT05588518

Propolis as a Treatment for Cervical Dentin Hypersensitivity

NCT05588518

Completed 75 enrolled King Khalid University
RandomizedParallel-groupDouble-blindTreatment

Summary

Fluoridated desensitizers the frequently used for the treatment of dentin hypersensitivity (DH) with Iontophoresis. This study aimed to evaluate and compare the immediate and long-term effects of 10% Propolis with 2% sodium fluoride and 1.23% acidulated phosphate fluoride when applied along with Iontophoresis for the treatment of cervical dentin hypersensitivity (DH). Single-center, parallel, and double-blinded randomized clinical trials were conducted on systemically healthy patients, complaining about DH, with at least two sites. 10% propolis, 2% Sodium Fluoride and 1.23% Acidulated Phosphate Fluoride were used as desensitizers along with the Iontophoresis. After applying specific stimuli any decrease in DH was measured at baseline before and after application, on the 14th day after use, and at 28th-day post-intervention time intervals.

Timeline

Start
2019-04-01
Primary completion
2020-02-01
Completion
2020-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Acidulated Phosphate Fluoride Unknown 1.23 %
Subject PROPOLIS WAX Traditional medicine (herbal / TCM) 10 %
Subject sodium fluoride Unknown 2 %

Indications