Drugs / PROPOLIS WAX
PROPOLIS WAX
also known as
propolis · Bee glue · Bee propolis · Brazilian Green Bee Propolis Liquid Extract · EEP · EPP-AF · Fengjiao · Propolis cera · +3 more
Trials 33 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 04 trials | ||||||
| Phase 0 | NCT06060340 | Oct 2023 → Jun 2024 | — | Cairo University | Unknown | No outcome recorded |
| Phase 0 | NCT05413096 | Jun 2021 → Oct 2022 | aphthous stomatitis | Al-Azhar University | Completed | No outcome recorded |
| Phase 0 | NCT04374006 | Nov 2019 → May 2020 | endometriosis of pelvic peritoneum | Indonesia University | Completed | No outcome recorded |
| Phase 0 | NCT04754763 | Jun 2018 → May 2019 | dentin sensitivity | Dow University of Health Sciences | Completed | No outcome recorded |
| Phase 12 trials | ||||||
| Phase 1 | NCT06029023 | Dec 2022 → Sep 2024 | exposure, dental pulp | Al-Azhar University | Completed | No outcome recorded |
| Phase 1 | NCT03615820 | Jan 2018 | — | British University In Egypt | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT04072341 | Aug → Dec 2019 | end stage renal failure | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| Phase 25 trials | ||||||
| Phase 2 | NCT07073092 | Jul → Dec 2025 overdue | chemotherapy-induced oral mucositis | Ain Shams University | Not yet recruiting | No outcome recorded |
| Phase 2 | NCT05870059 | Feb → Jul 2022 | chronic periodontitis | Ziauddin University | Completed | No outcome recorded |
| Phase 2 | NCT03580135 | Nov 2018 → Jan 2019 | dental pulp disorder | Cairo University | Unknown | No outcome recorded |
| Phase 2 | NCT03416127 | Jan 2018 → Dec 2019 | type 2 diabetes mellitus | University of Guadalajara | Completed | No outcome recorded |
| Phase 2 | NCT03812315 | Dec 2017 → Feb 2019 | dental caries | Nourhan M.Aly | Completed | No outcome recorded |
| Phase 2/33 trials | ||||||
| Phase 2/3 | NCT06455007 | Jan 2019 → Jan 2022 | — | Murat Sutcu | Completed | No outcome recorded |
| Phase 2/3 | NCT04819867 | Dec 2018 → Mar 2019 | dentin sensitivity | Dow University of Health Sciences | Completed | No outcome recorded |
| Phase 2/3 | NCT03394729 | Sep 2017 → Oct 2020 | — | Federal University of Rio de Janeiro | Completed | No outcome recorded |
| Phase 33 trials | ||||||
| Phase 3 | NCT05974748 | Apr → Aug 2023 | pulpitis | Dow University of Health Sciences | Completed | No outcome recorded |
| Phase 3 | NCT03723980 | Nov 2017 → Apr 2018 | — | Juzer Shabbir Saifee | Completed | No outcome recorded |
| Phase 3 | NCT00231218 | Jan → Mar 2006 | common cold, gastroenteritis | The Cleveland Clinic | Completed | No outcome recorded |
| Phase 44 trials | ||||||
| Phase 4 | NCT07683520 | Oct 2025 → Jun 2026 | chronic apical periodontitis | Ain Shams University | Completed | No outcome recorded |
| Phase 4 | NCT06903546 | Mar → Jun 2025 overdue | type 2 diabetes mellitus | Indonesia University | Recruiting | No outcome recorded |
| Phase 4 | NCT03533231 | Jan 2015 → Oct 2017 | acute apical periodontitis, dental abscess, dental pulp necrosis | Tariq Yehia | Completed | No outcome recorded |
| Phase 4 | NCT02794506 | Jun → Dec 2014 | chronic periodontitis, type 2 diabetes mellitus | Mohamed Anees | Completed | No outcome recorded |
| Phase not applicable11 trials | ||||||
| — | NCT07578311 | Jul 2026 → Jan 2027 expected | — | Minia University | Not yet recruiting | No outcome recorded |
| — | NCT07099482 | May → Aug 2026 overdue | type 1 diabetes mellitus, type 2 diabetes mellitus, ulcer of lower limbs | Sinai University | Not yet recruiting | No outcome recorded |
| — | NCT06158451 | Mar → Aug 2024 | periapical periodontitis | Cairo University | Unknown | No outcome recorded |
| — | NCT05569590 | May → Dec 2021 | — | Dow University of Health Sciences | Completed | No outcome recorded |
| — | NCT04277182 | Sep 2020 | — | Izmir Katip Celebi University | Completed | No outcome recorded |
| — | NCT05588518 | Apr 2019 → Feb 2020 | dentin sensitivity | King Khalid University | Completed | No outcome recorded |
| — | NCT04032548 | Feb → Mar 2019 | gingivitis | Mahsa University | Completed | No outcome recorded |
| — | NCT03591172 | Sep → Nov 2018 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT04983524 | Oct 2015 → May 2018 | chronic pain syndrome, dental pulp necrosis | Cairo University | Completed | No outcome recorded |
| — | NCT01943877 | Dec 2012 → Aug 2013 | chronic periodontitis | Rajarajeswari Dental College & Hospital | Unknown | No outcome recorded |
| — | NCT01237782 | Sep 2010 → Jun 2011 | denture stomatitis, oral candidiasis | Raphael Freitas de Souza | Completed | No outcome recorded |
Also used as a comparator or background therapy in 5 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 22 trials | ||||||
| Phase 2 | NCT02766036 Comparator | Dec 2016 → Feb 2018 | chronic kidney disease | University of Sao Paulo General Hospital | Completed | No outcome recorded |
| Phase 2 | NCT01375088 Comparator | Oct 2010 → Mar 2011 | mucositis | Mashhad University of Medical Sciences | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT01750801 Comparator | Feb 2013 → Jul 2014 | gingivitis, periodontitis | Federal University of Minas Gerais | Unknown | No outcome recorded |
| Phase not applicable2 trials | ||||||
| — | NCT06663995 Comparator | Sep 2023 → Jun 2024 overdue | periodontitis | Ain Shams University | Active not recruiting | No outcome recorded |
| — | NCT05400031 Comparator | Jun 2022 → May 2023 | chemotherapy-induced oral mucositis | Izmir Katip Celebi University | Completed | No outcome recorded |
Evidence & citations 15 cited values
Every value below carries the sentence it was read from. 40 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | PROPOLIS WAX | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗ |
| Known as | Bee glue | “Bee glue” NCT03723980 ↗ |
| Known as | Bee propolis | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗ |
| Known as | Brazilian Green Bee Propolis Liquid Extract | “Propolis liquid (Brazilian Green Bee Propolis Liquid Extract, Uniflora®) and Zinc oxide powder will be mixed and added after minimal instrumentation until size 20 to remove all...” NCT06158451 ↗ |
| Known as | EEP | “Ethanol extract of raw propolis (EEP; ElEzaby Co. Labs, Cairo, Egypt.)” NCT03533231 ↗ |
| Known as | EPP-AF | “We assessed the safety and impact of a standardized Brazilian green propolis extract (EPP-AF®) on the inflammatory status in patients under conventional HD.” PMID 36457860 ↗ Nov 2022 |
| Known as | Fengjiao | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗ |
| Known as | propolis | “Niosomal PPE oromucoadhesive film in which Propolis entrapped in niosomal vesicles and incorporated in oromucoadhesive film” NCT03615820 ↗36“The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.” NCT04983524 ↗ “To prepare 100 ml of propolis extract gel, 1 g of propolis (Imtnan, Egypt) was extracted using 18.22 ml ethanol.” NCT06663995 ↗ “A proprietary denture cleanser with propolis as the active agent.” NCT01237782 ↗ “10% Propolis will be applied topically for 21 days.” NCT04277182 ↗ |
| Known as | Propolis cera | ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗ |
| Known as | Propolis Extract | ClinicalTrials.gov intervention name — accepted as the source's own label NCT07578311 ↗ |
| Known as | Spa Dent | “Propolis solution: Spa Dent (Nissin Dental Products Inc., Kyoto, Japan).” NCT01237782 ↗ |
| Known as | Uniflora | “Propolis liquid (Brazilian Green Bee Propolis Liquid Extract, Uniflora®) and Zinc oxide powder will be mixed and added after minimal instrumentation until size 20 to remove all...” NCT06158451 ↗ |
| Action | Inhibit | “The immunological effect of propolis is generated through immune suppression directly and decreasing cytokine production” NCT04374006 ↗ |
| Modality | Traditional medicine (herbal / TCM) | “In homeopathic practices it is widely used as an anti-inflammatory and antiseptic agent.” NCT04819867 ↗ |
| Route | Oral | “15 ml mouth wash 3 times a day for the whole period of radiotherapy for 5 min swish and then swallow” NCT01375088 ↗ |