Drugs / PROPOLIS WAX
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PROPOLIS WAX

Traditional medicine (herbal / TCM)

Developed for
type 2 diabetes mellitus · chronic periodontitis · dentin sensitivity · dental pulp necrosis · acute apical periodontitis · aphthous stomatitis · chemotherapy-induced oral mucositis · chronic apical periodontitis
+18 more · chronic pain syndrome · common cold · dental abscess · dental caries · dental pulp disorder · denture stomatitis · end stage renal failure · endometriosis of pelvic peritoneum · exposure, dental pulp · gastroenteritis · gingivitis · oral candidiasis · periapical periodontitis · pulpitis · ulcer of lower limbs · chronic kidney disease · mucositis · periodontitis
Investigated by
Cairo University · Dow University of Health Sciences · Ain Shams University · Al-Azhar University · Indonesia University · Alagoas State University of Health Science , Maceió , Brazil.
+24 more · Alexandria University · British University In Egypt · Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. · Federal University of Rio de Janeiro · Hospital Sao Rafael · Izmir Katip Celebi University · Juzer Shabbir Saifee · King Khalid University · Mahsa University · Mansoura University · Minia University · Mohamed Anees · Murat Sutcu · Nourhan M.Aly · October 6 University · Rajarajeswari Dental College & Hospital · Raphael Freitas de Souza · Sinai University · São Paulo Research Foundation · Tariq Yehia · The Cleveland Clinic · University of Guadalajara · University of Sao Paulo General Hospital · Ziauddin University

Trials 33

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 04 trials
Phase 0 NCT06060340 Oct 2023 → Jun 2024 — Cairo University Unknown No outcome recorded
Phase 0 NCT05413096 Jun 2021 → Oct 2022 aphthous stomatitis Al-Azhar University Completed No outcome recorded
Phase 0 NCT04374006 Nov 2019 → May 2020 endometriosis of pelvic peritoneum Indonesia University Completed No outcome recorded
Phase 0 NCT04754763 Jun 2018 → May 2019 dentin sensitivity Dow University of Health Sciences Completed No outcome recorded
Phase 12 trials
Phase 1 NCT06029023 Dec 2022 → Sep 2024 exposure, dental pulp Al-Azhar University Completed No outcome recorded
Phase 1 NCT03615820 Jan 2018 — British University In Egypt Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT04072341 Aug → Dec 2019 end stage renal failure University of Sao Paulo General Hospital Completed No outcome recorded
Phase 25 trials
Phase 2 NCT07073092 Jul → Dec 2025 overdue chemotherapy-induced oral mucositis Ain Shams University Not yet recruiting No outcome recorded
Phase 2 NCT05870059 Feb → Jul 2022 chronic periodontitis Ziauddin University Completed No outcome recorded
Phase 2 NCT03580135 Nov 2018 → Jan 2019 dental pulp disorder Cairo University Unknown No outcome recorded
Phase 2 NCT03416127 Jan 2018 → Dec 2019 type 2 diabetes mellitus University of Guadalajara Completed Mixed
Phase 2 NCT03812315 Dec 2017 → Feb 2019 dental caries Nourhan M.Aly Completed No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT06455007 Jan 2019 → Jan 2022 — Murat Sutcu Completed No outcome recorded
Phase 2/3 NCT04819867 Dec 2018 → Mar 2019 dentin sensitivity Dow University of Health Sciences Completed No outcome recorded
Phase 2/3 NCT03394729 Sep 2017 → Oct 2020 — Federal University of Rio de Janeiro Completed No outcome recorded
Phase 33 trials · 1 missed
Phase 3 NCT05974748 Apr → Aug 2023 pulpitis Dow University of Health Sciences Completed No outcome recorded
Phase 3 NCT03723980 Nov 2017 → Apr 2018 — Juzer Shabbir Saifee Completed Missed primary
Phase 3 NCT00231218 Jan → Mar 2006 common cold, gastroenteritis The Cleveland Clinic Completed No outcome recorded
Phase 44 trials
Phase 4 NCT07683520 Oct 2025 → Jun 2026 chronic apical periodontitis Ain Shams University Completed No outcome recorded
Phase 4 NCT06903546 Mar → Jun 2025 overdue type 2 diabetes mellitus Indonesia University Recruiting No outcome recorded
Phase 4 NCT03533231 Jan 2015 → Oct 2017 acute apical periodontitis, dental abscess, dental pulp necrosis Tariq Yehia Completed No outcome recorded
Phase 4 NCT02794506 Jun → Dec 2014 chronic periodontitis, type 2 diabetes mellitus Mohamed Anees Completed No outcome recorded
Phase not applicable11 trials
— NCT07578311 Jul 2026 → Jan 2027 expected — Minia University Not yet recruiting No outcome recorded
— NCT07099482 May → Aug 2026 overdue type 1 diabetes mellitus, type 2 diabetes mellitus, ulcer of lower limbs Sinai University Not yet recruiting No outcome recorded
— NCT06158451 Mar → Aug 2024 periapical periodontitis Cairo University Unknown No outcome recorded
— NCT05569590 May → Dec 2021 — Dow University of Health Sciences Completed No outcome recorded
— NCT04277182 Sep 2020 — Izmir Katip Celebi University Completed No outcome recorded
— NCT05588518 Apr 2019 → Feb 2020 dentin sensitivity King Khalid University Completed No outcome recorded
— NCT04032548 Feb → Mar 2019 gingivitis Mahsa University Completed No outcome recorded
— NCT03591172 Sep → Nov 2018 — Cairo University Unknown No outcome recorded
— NCT04983524 Oct 2015 → May 2018 chronic pain syndrome, dental pulp necrosis Cairo University Completed No outcome recorded
— NCT01943877 Dec 2012 → Aug 2013 chronic periodontitis Rajarajeswari Dental College & Hospital Unknown No outcome recorded
Comparator or background therapy5 trials
Phase 2 NCT02766036 Comparator Dec 2016 → Feb 2018 chronic kidney disease University of Sao Paulo General Hospital Completed No outcome recorded
Phase 2 NCT01375088 Comparator Oct 2010 → Mar 2011 mucositis Mashhad University of Medical Sciences Completed No outcome recorded
Phase 3 NCT01750801 Comparator Feb 2013 → Jul 2014 gingivitis, periodontitis Federal University of Minas Gerais Unknown No outcome recorded
— NCT06663995 Comparator Sep 2023 → Jun 2024 overdue periodontitis Ain Shams University Active not recruiting No outcome recorded
— NCT05400031 Comparator Jun 2022 → May 2023 chemotherapy-induced oral mucositis Izmir Katip Celebi University Completed No outcome recorded

Evidence & citations 15 cited values

Every value below carries the sentence it was read from. 40 sources stand behind the page.

FieldValueCited text
Known as PROPOLIS WAX ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗
Known as Bee glue “Bee glue” NCT03723980 ↗
Known as Bee propolis ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗
Known as Brazilian Green Bee Propolis Liquid Extract “Propolis liquid (Brazilian Green Bee Propolis Liquid Extract, Uniflora®) and Zinc oxide powder will be mixed and added after minimal instrumentation until size 20 to remove all...” NCT06158451 ↗
Known as EEP “Ethanol extract of raw propolis (EEP; ElEzaby Co. Labs, Cairo, Egypt.)” NCT03533231 ↗
Known as EPP-AF “We assessed the safety and impact of a standardized Brazilian green propolis extract (EPP-AF®) on the inflammatory status in patients under conventional HD.” PMID 36457860 ↗ Nov 2022
Known as Fengjiao ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗
Known as Propolis “Niosomal PPE oromucoadhesive film in which Propolis entrapped in niosomal vesicles and incorporated in oromucoadhesive film” NCT03615820 ↗
36

“The clinical trial tests the effect of propolis versus calcium hydroxide on pain in patients with necrotic teeth.” NCT04983524 ↗

“To prepare 100 ml of propolis extract gel, 1 g of propolis (Imtnan, Egypt) was extracted using 18.22 ml ethanol.” NCT06663995 ↗

“A proprietary denture cleanser with propolis as the active agent.” NCT01237782 ↗

“10% Propolis will be applied topically for 21 days.” NCT04277182 ↗

NCT04374006 ↗

NCT03812315 ↗

NCT03591172 ↗

NCT03416127 ↗

NCT03394729 ↗

NCT05569590 ↗

Show 26 more sources

Known as Propolis cera ChEMBL registry synonym — accepted as the source's own label CHEMBL4298075 ↗
Known as Propolis Extract ClinicalTrials.gov intervention name — accepted as the source's own label NCT07578311 ↗
Known as Spa Dent “Propolis solution: Spa Dent (Nissin Dental Products Inc., Kyoto, Japan).” NCT01237782 ↗
Known as Uniflora “Propolis liquid (Brazilian Green Bee Propolis Liquid Extract, Uniflora®) and Zinc oxide powder will be mixed and added after minimal instrumentation until size 20 to remove all...” NCT06158451 ↗
Action Inhibit “The immunological effect of propolis is generated through immune suppression directly and decreasing cytokine production” NCT04374006 ↗
Modality Traditional medicine (herbal / TCM) “In homeopathic practices it is widely used as an anti-inflammatory and antiseptic agent.” NCT04819867 ↗
Route Oral “15 ml mouth wash 3 times a day for the whole period of radiotherapy for 5 min swish and then swallow” NCT01375088 ↗