drugset / Trial / NCT05569590

Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.

NCT05569590

Completed 90 enrolled Dow University of Health Sciences
RandomizedParallel-groupDouble-blindPrevention

Summary

This study was conducted to evaluate the efficacy of desensitizing agent Propolis, after an in -office vital tooth bleaching and to compare its desensitizing effect to traditionally used desensitizing agent fluoride varnish. Methods: Considering the inclusion and exclusion criteria 90 patients will be selected at the OPD of Dow University of Health Sciences Ojha campus with mild to moderate discoloration and randomly divided in to three groups group A control group (fluoride varnish) group B Propolis and group C Propolis mixed with bleaching agent. After performing the bleaching procedure respective desensitizing agent was applied to each group for 10 minutes. Visual analogue scale and Schiff's scale were used to assess the sensitivity after completion of treatment. Subjective non stimulated assessment of sensitivity was done by using the visual analogue scale from day 1 till day 7 on given Performa and Objective stimulated assessment of sensitivity was done at the dental office on day 1 right after the procedure and at day 7 on follow-up after one week. Kruskal-Wallis test was applied to check median pain score and sensitivity difference between and among the groups. Mann-Whitney U test was applied to check further pairwise comparison between the groups.

Timeline

Start
2021-05-14
Primary completion
2021-12-25
Completion
2022-06-22

Drugs

EvaluationDrugModalityDoseRoute
Subject PROPOLIS WAX Traditional medicine (herbal / TCM)
Background Hydrogen Peroxide Small molecule

Indications

No indication recorded.