drugset / Trial / NCT05974748

Role of Propolis Endodontic Irrigant on Post-Operative Pain

NCT05974748

Phase 3 Completed 44 enrolled Dow University of Health Sciences
RandomizedParallel-groupDouble-blindPrevention

Summary

The goal of this clinical trial is to compare propolis and sodium hypochlorite as endodontic irrigants in patients presenting with symptomatic irreversible pulpitis. . The main question it aims to answer is: • if there is any analgesic effects of 20% Propolis compared with 5.25% NaOCl on the intensity of post-operative pain in patients with symptomatic irreversible pulpitis using VAS pain score. Participants will undergo root canal treatment of their teeth using either 20% propolis solution or 5.25% NaOCl in their first visit of a multi-visit root canal treatment. Researchers will compare 20% Propolis and 5.25% NaOCl to see reduction in Intensity of Post-Operative Pain using visual analogue scale over 72 hour duration.

Timeline

Start
2023-04-01
Primary completion
2023-08-15
Completion
2023-08-15

Drugs

EvaluationDrugModalityDoseRoute
Subject PROPOLIS WAX Traditional medicine (herbal / TCM) 3 ml Other
Subject PROPOLIS WAX Traditional medicine (herbal / TCM) 20 % Other
Comparator Sodium Hypochlorite Unknown 3 ml Other
Comparator Sodium Hypochlorite Unknown 5.25 % Other

Indications