drugset / Trial / NCT03416127

Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus

NCT03416127

Phase 2 Completed 36 enrolled University of Guadalajara
RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this study was to evaluate the effect of propolis or metformin on glycemic control in patients with type 2 diabetes mellitus without pharmacological treatment. All patients received for 12 weeks propolis, metformin or placebo. Fasting serum glucose, 2-h serum glucose after oral glucose tolerance test, glycated hemoglobin A1c, a metabolic profile, areas under the curve of glucose and insulin, insulinogenic index, Stumvoll index, and Matsuda index were measured.

Timeline

Start
2018-01-30
Primary completion
2019-12-20
Completion
2019-12-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 850 mg
Subject PROPOLIS WAX Traditional medicine (herbal / TCM) 300 mg