drugset / Trial / NCT07419737
Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste
RandomizedParallel-groupTriple-blindPrevention
Summary
This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.
Timeline
- Start
- 2024-10-16
- Primary completion
- 2024-12-04
- Completion
- 2024-12-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium fluoride | Unknown | 0.243 % | Oral |
| Subject | stannous fluoride | Small molecule | 0.454 % | Oral |