drugset / Trial / NCT07419737

Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste

NCT07419737

Completed 91 enrolled Church & Dwight Company, Inc.
RandomizedParallel-groupTriple-blindPrevention

Summary

This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.

Timeline

Start
2024-10-16
Primary completion
2024-12-04
Completion
2024-12-04

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium fluoride Unknown 0.243 % Oral
Subject stannous fluoride Small molecule 0.454 % Oral