drugset / Trial / NCT00708305

Evaluation of Plaque Fluid Fluoride Retention From Fluoride Toothpastes

NCT00708305 ↗

Phase 3 Completed 65 enrolled GlaxoSmithKline
RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to investigate the efficacy of different sodium fluoride (NaF) containing toothpastes in prevention of dental caries. Change from baseline fluoride data at various time points up to four hours after a single brushing with NaF containing toothpastes will be evaluated.

Timeline

Start
2008-06
Primary completion
2008-10
Completion
2008-10

Outcome

Missed primary endpoint

registry analysis (superiority or other test); NaF Toothpaste(1450 Ppm F) vs NaF Toothpaste (1400 Ppm F); p = 0.9762; Adjusted Mean Difference 0.00 (95% CI -0.21 to 0.20); NCT00708305 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium fluoride Unknown 1400 ppm Topical
Subject sodium fluoride Unknown 1450 ppm Topical

Indications