Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth

Phase 0 Completed 66 enrolled Alexandria University

RandomizedParallel-groupDouble-blindTreatment

Summary

the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode. The secondary aim of the study is to compare their antibacterial effect against streptococcus mutans and their effect on reducing the size of the lesions.

Timeline

Start: 2023-08-15
Primary completion: 2024-10-15
Completion: 2024-10-15

Publications

Background Mekky AI, Dowidar KML, Talaat DM. Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride Varnish in Remineralization of Early Carious Lesions in Primary Dentition: Randomized Clinical Trial. Pediatr Dent. 2021 Jan 15;43(1):17-23.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Casein phosphopeptide amorphous calcium phosphate	Peptide	—	—
Subject	P11-4	Peptide	0.05 %	—
Comparator	sodium fluoride	Unknown	5 %	—

Indications

No indication recorded.