drugset / Trial / NCT05654662
A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
RandomizedParallel-groupSingle-blindTreatment
Summary
The main goal of this study is to evaluate and compare the efficacy of an on-market dentifrice containing 67 percent (%) sodium bicarbonate and 0.31% sodium fluoride to a reference regular fluoride dentifrice on treating gingival bleeding and gingival inflammation as well as reducing plaque accumulation in population with gingivitis after 12 weeks use.
Timeline
- Start
- 2023-02-20
- Primary completion
- 2023-11-30
- Completion
- 2023-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium bicarbonate | Diagnostic / imaging agent | 67 % | Topical |
| Subject | sodium fluoride | Unknown | 0.1 % | Topical |
| Subject | sodium fluoride | Unknown | 0.31 % | Topical |
| Comparator | sodium monofluorophosphate | Unknown | 0.76 % | Topical |