drugset / Trial / NCT07478640

Bioadhesive Film of Acmella Oleracea (Jambu) in the Reduction of Post-bleaching Dental Sensitivity Caused by Bleaching With 35% Hydrogen Peroxide.

NCT07478640

Phase 3 Completed 72 enrolled Federal University of Pará
RandomizedParallel-groupSingle-blindTreatment

Summary

Despite the wide range of desensitizing agents available on the market, there is still no gold standard treatment that is fully effective in managing sensitivity by dental bleaching. In this context, a bioadhesive film containing Acmella oleracea (jambu)-a natural product with anti-inflammatory and, most notably, analgesic properties-may represent an effective alternative for controlling this discomfort. Therefore, this project aims to clinically evaluate the efficacy of an Acmella oleracea extract bioadhesive film on tooth sensitivity induced by 35% hydrogen peroxide bleaching.

Timeline

Start
2024-04-01
Primary completion
2025-06-22
Completion
2026-03-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Acmella Oleracea Unknown Topical
Comparator Potassium Nitrate Other / unclassified 5 % Topical
Comparator sodium fluoride Unknown 2 % Topical

Indications