drugset / Trial / NCT01005966
In Situ Caries Model of Fluoride Toothpastes
RandomizedCrossoverSingle-blindTreatment
Summary
This study is to evaluate the effect of fluoride dentrifrices on enamel with artificial caries lesions in an in situ model
Timeline
- Start
- 2008-11
- Primary completion
- 2009-03
- Completion
- 2009-03
Outcome
Missed primary endpoint
registry analysis (superiority or other test); NaF Toothpaste (1426ppmF) vs AmF Toothpaste (1400ppmF); p = 0.2117; Adjusted Mean Difference -3.01 (95% CI -7.75 to 1.73); ANOVA; NCT01005966 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amine Fluoride | Unknown | — | — |
| Subject | Fluoride | Other / unclassified | 675 ppm | — |
| Comparator | Sodium monofluorophosphate/Sodium Fluoride | Unknown | — | — |
| Subject | sodium fluoride | Unknown | — | — |