drugset / Trial / NCT03383783
Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model
RandomizedCrossoverDouble-blindOther
Summary
The purpose of this study is to evaluate the fluoride dose response of different dentifrice fluoride concentrations - 0, 250, 500 and 1100 ppm fluoride of our existing in situ model involving the use of human enamel specimens placed in the buccal flange area of the subjects partial denture with the modified model involving placement of bovine enamel specimens in a denture tooth location.
Timeline
- Start
- 2017-12-19
- Primary completion
- 2018-05-02
- Completion
- 2018-05-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium fluoride | Unknown | 250 ppm | Topical |
| Subject | sodium fluoride | Unknown | 500 ppm | Topical |
| Subject | sodium fluoride | Unknown | 1100 ppm | Topical |