drugset / Trial / NCT02341352
Three Measures for the Prevention of Carious Lesions in Preschool Children
Phase 3
Unknown
500 enrolled
Zhejiang University
Hangzhou Occupational Disease Prevention Hospital · collab
RandomizedParallel-groupDouble-blindHealth-services research
Summary
Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children
Timeline
- Start
- 2013-04
- Primary completion
- 2015-04
- Completion
- 2015-06
Publications
- Zhang J, Su L, Wang Y, Deng S. Improved High-Throughput Sequencing of the Human Oral Microbiome: From Illumina to PacBio. Can J Infect Dis Med Microbiol. 2020 Dec 11;2020:6678872. doi: 10.1155/2020/6678872. eCollection 2020.
- Wang Y, Wang S, Wu C, Chen X, Duan Z, Xu Q, Jiang W, Xu L, Wang T, Su L, Wang Y, Chen Y, Zhang J, Huang Y, Tong S, Zhou C, Deng S, Qin N. Oral Microbiome Alterations Associated with Early Childhood Caries Highlight the Importance of Carbohydrate Metabolic Activities. mSystems. 2019 Nov 5;4(6):e00450-19. doi: 10.1128/mSystems.00450-19.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Immunoglobulin Yolk | Protein / enzyme biologic | — | Oral |
| Subject | sodium fluoride | Unknown | 50 mg/ml | — |