Stannous Fluoride Toothpaste for Reduction and Treatment of Gingivitis

Summary

This study evaluated the efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste in reducing gingivitis, bleeding, and plaque over a 12-week period. A total of 132 subjects were randomized to one of two treatment groups and assessed at baseline and at Weeks 2, 4, 8, and 12 using standardized clinical indices, including the Modified Gingival Index (MGI), Bleeding Index (BI), and Plaque Index (PI).

Timeline

Start

2025-03-17

Primary completion

2025-06-13

Completion

2025-06-13

Drugs

Indications