drugset / Trial / NCT02195583
The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
RandomizedCrossoverQuadruple-blindTreatment
Summary
This study will evaluate the effect of experimental sodium fluoride-silica dentifrice formulations, with and without zinc, on remineralization of enamel in situ. Following the remineralization phase, the acid resistance of the new mineral formed will be assessed. Fluoride uptake during the remineralization phase will also be measured.
Timeline
- Start
- 2014-06
- Primary completion
- 2014-08
- Completion
- 2014-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sodium fluoride | Unknown | 250 ppm | — |
| Subject | sodium fluoride | Unknown | 1150 ppm | — |
| Subject | sodium fluoride | Unknown | 1426 ppm | — |
Indications
No indication recorded.