Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion

Summary

An in situ model will be used to evaluate and compare enamel remineralization of bovine enamel specimens.

Timeline

Start

2009-08

Primary completion

2009-10

Completion

2009-10

Outcome

Met primary endpoint

registry Test Dentifrice + Test MR vs Test Dentifrice + Sterile Water Rinse; p <0.0001; Adjusted Mean Difference 11.66 (95% CI 7.09 to 16.24) NCT01128972 ↗

Publications

• Background Maggio B, Guibert RG, Mason SC, Karwal R, Rees GD, Kelly S, Zero DT. Evaluation of mouthrinse and dentifrice regimens in an in situ erosion remineralisation model. J Dent. 2010 Nov;38 Suppl 3:S37-44. doi: 10.1016/S0300-5712(11)70007-0.

Drugs

Indications