Antimicrobial Agent for Reducing Bacteria in Aerosols and Oral Cavity
Summary
The primary objective of this study will be to evaluate the effect of two week pre-surgical rinsing with an antimicrobial mouthrinse containing 0.2% w/v Chlorhexidine digluconate on the total number of plaque bacteria in the mouth 3 days post implant surgery. The study will be conducted at Eastman Clinical Investigation Centre (ECIC), University College London (UCL) Eastman Dental Institute. Participants will be those who require a single and simple surgical implant to be placed, and will be recruited from new patient referrals within the Eastman Dental Hospital
Timeline
- Start
- 2015-02-01
- Primary completion
- 2015-06-01
- Completion
- 2016-02-29
Outcome
Missed primary endpoint
registry Test and Reference Product vs Reference Product; p = 0.2965; Least square (LS) Mean difference 0.20 (95% CI -0.18 to 0.58); ANCOVA NCT02319668 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Chlorhexidine gluconate | Other / unclassified | 0.2 % | Other |
| Background | sodium fluoride | Unknown | — | Other |
Indications
No indication recorded.