Cannabinoids, Neural Synchrony, and Information Processing

Phase 0 Completed 42 enrolled Yale University National Institute on Drug Abuse (NIDA) · collab

RandomizedCrossoverQuadruple-blindBasic science

Summary

The study examines the effects of delta-9-tetrahydrocannabinol (Δ9-THC), the principal active ingredient of cannabis, on neural synchrony. Neural synchrony is studied using electroencephalography (EEG).

Timeline

Start: 2008-02-25
Primary completion: 2012-12-03
Completion: 2012-12-03

Publications

Ranganathan M, Radhakrishnan R, Addy PH, Schnakenberg-Martin AM, Williams AH, Carbuto M, Elander J, Pittman B, Andrew Sewell R, Skosnik PD, D'Souza DC. Tetrahydrocannabinol (THC) impairs encoding but not retrieval of verbal information. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):176-183. doi: 10.1016/j.pnpbp.2017.06.019. Epub 2017 Jun 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	delta-9-tetrahydrocannabinol	Other / unclassified	0.0015 mg/kg	Intravenous
Comparator	delta-9-tetrahydrocannabinol	Other / unclassified	0.015 mg/kg	Intravenous
Comparator	delta-9-tetrahydrocannabinol	Other / unclassified	0.03 mg/kg	Intravenous

Cannabinoids, Neural Synchrony, and Information Processing

Summary

Timeline

Publications

Drugs

Indications