drugset / Trial / NCT00709592
Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT
RandomizedParallel-groupOpen-labelTreatment
Summary
One of two different doses of thymoglobulin will allow bone marrow engraftment with minimal Graft-versus-Host Disease and allow adequate immune response to allow the transplanted stem cells to replace the tumor cells.
Timeline
- Start
- 2008-07-21
- Primary completion
- 2014-02-15
- Completion
- 2017-06-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Thymoglobulin | Protein / enzyme biologic | 1.7 mg/kg | Intravenous |
| Subject | Thymoglobulin | Protein / enzyme biologic | 2.5 mg/kg | Intravenous |
| Background | Mycophenolate Mofetil | Small molecule | — | Oral |
| Background | Tacrolimus | Small molecule | — | Oral |