Drugs / Thymoglobulin
last change Aug 2026 re-read 2 minutes ago

Thymoglobulin

Protein / enzyme biologic

Developed for
myelodysplastic syndrome · acute myeloid leukemia · aplastic anemia · graft versus host disease · hematopoietic and lymphoid cell neoplasm · leukemia · transplant rejection · disease related to hematopoietic stem cell transplant
+47 more · chronic myeloid leukemia · acute lymphoblastic leukemia · lymphoma · plasma cell myeloma · sickle cell disease · acquired aplastic anemia · cancer · end stage renal failure · immunodeficiency disease · liver disorder · acute graft versus host disease · bone marrow failure syndrome · chronic lymphocytic leukemia/small lymphocytic lymphoma · diabetes mellitus · hematologic disorder · Hodgkins lymphoma · kidney failure · neuroblastoma · paroxysmal nocturnal hemoglobinuria · type 1 diabetes mellitus · acquired thrombocytopenia · acute transplant rejection · anemia · autosomal genetic disease · beta thalassemia · disease of orbital part of eye adnexa · engraftment syndrome · hemophagocytic syndrome · histiocytosis · idiopathic aplastic anemia · IgA glomerulonephritis · inborn errors of metabolism · juvenile myelomonocytic leukemia · liver failure · lymphoid hemopathy · metabolic disease · myopathy · osteopetrosis · primary acquired red cell aplasia · refractory plasma cell neoplasm · relapsing-remitting multiple sclerosis · severe combined immunodeficiency · systemic sclerosis · thalassemia · Wiskott-Aldrich syndrome · impaired renal function disease · ischemic disease
Investigated by
Genzyme, a Sanofi Company · M.D. Anderson Cancer Center · Peking University People's Hospital · The Korean Society of Pediatric Hematology Oncology · Washington University School of Medicine · Columbia University
+109 more · Institut Paoli-Calmettes · Sanofi · University of Miami · University of Nebraska · Association for Training, Education, and Research in Hematology, Immunology, and Transplantation · City of Hope Medical Center · Fresenius AG · Institute of Hematology & Blood Diseases Hospital, China · Masonic Cancer Center, University of Minnesota · Nantes University Hospital · National Institute of Allergy and Infectious Diseases (NIAID) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Neovii Biotech · Novartis · St. Jude Children's Research Hospital · The Cleveland Clinic · University of Cincinnati · medac GmbH · Agence de La Biomédecine · Alberta Health services · Amgen · Ann & Robert H Lurie Children's Hospital of Chicago · Astellas Pharma Inc · Barbara Ann Karmanos Cancer Institute · Belgian Hematological Society · Brigham and Women's Hospital · California Institute for Regenerative Medicine (CIRM) · Canadian Institutes of Health Research (CIHR) · Children's Discovery Institute · Children's Hospital Medical Center, Cincinnati · Chinese PLA General Hospital · Clinical Trials in Organ Transplantation · Coordinación de Investigación en Salud, Mexico · Emory University · European Society for Blood and Marrow Transplantation · Fondazione IRCCS Policlinico San Matteo di Pavia · Franco Locatelli · Fred Hutchinson Cancer Center · Fujian Medical University · Georgetown University · Hadassah Medical Organization · Hoffmann-La Roche · Hospices Civils de Lyon · Hospital Clinic of Barcelona · Hospital Geral de Fortaleza · Hospital de Santa Maria, Portugal · Hospital do Rim e Hipertensão · Institut Klinické a Experimentální Medicíny · Institute for Clinical and Experimental Medicine · Instituto de Investigación Hospital Universitario La Paz · Italian Association for Pediatric Hematology Oncology · Johns Hopkins University · King Faisal Specialist Hospital & Research Center · King's College Hospital NHS Trust · Lahey Clinic · McMaster University · Medical University of Silesia · Millennium Pharmaceuticals, Inc. · Ministry of Health, Czech Republic · Ministry of Health, France · Nagoya University · National Cancer Institute (NCI) · National Heart, Lung, and Blood Institute (NHLBI) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · National Institute of Blood Disease Center, Pakistan · New York Medical College · Northwestern University · Otsuka America Pharmaceutical · Peking Union Medical College Hospital · Pfizer · Prof. Dr. Petra Reinke · Prof. Dr. med. Wolfgang Bethge · Providence Health & Services · Rising Tide Foundation · all 115 on the full record

Trials 113 · started per year

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20002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT04776850 Dec 2020 → Dec 2022 beta-thalassemia major, sickle cell disease, sickle cell-beta plus-thalassemia, sickle cell-beta zero-thalassemia M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 17 trials
Phase 1 NCT07052370 Sep 2025 → Dec 2028 expected hematopoietic and lymphoid system neoplasm St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 1 NCT03249831 Jan 2019 → Jan 2027 expected sickle cell disease, thalassemia City of Hope Medical Center Active not recruiting No outcome recorded
Phase 1 NCT00545519 Oct 2006 → Mar 2008 refractory plasma cell neoplasm Washington University School of Medicine Completed No outcome recorded
Phase 1 NCT00317798 Apr 2006 → Apr 2011 plasma cell myeloma, poisoning University of Rochester Completed No outcome recorded
Phase 1 NCT00278564 Sep 2005 → Jul 2016 myopathy Northwestern University Terminated No outcome recorded
Phase 1 NCT00670410 Nov 2003 → Dec 2010 neuroblastoma Columbia University Terminated No outcome recorded
Phase 1 NCT00040651 Jul 2002 → Mar 2007 systemic sclerosis National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) Terminated No outcome recorded
Phase 1/28 trials
Phase 1/2 NCT06158828 Nov 2024 → Sep 2028 expected acute myeloid leukemia by FAB classification, childhood acute myeloid leukemia Washington University School of Medicine Recruiting No outcome recorded
Phase 1/2 NCT01106157 Apr 2010 → Jan 2015 type 1 diabetes mellitus University of Florida Completed No outcome recorded
Phase 1/2 NCT00679536 May 2008 → May 2015 leukemia Ann & Robert H Lurie Children's Hospital of Chicago Unknown No outcome recorded
Phase 1/2 NCT00801931 Sep 2007 → May 2009 anemia, immunodeficiency disease, leukemia, lymphoma +1 Columbia University Terminated No outcome recorded
Phase 1/2 NCT00885833 Feb 2007 → Mar 2012 Wiskott-Aldrich syndrome The Korean Society of Pediatric Hematology Oncology Completed No outcome recorded
Phase 1/2 NCT00409695 Dec 2006 → Aug 2007 acute graft versus host disease M.D. Anderson Cancer Center Terminated No outcome recorded
Phase 1/2 NCT00887042 Jun 2006 → May 2012 acute myeloid leukemia The Korean Society of Pediatric Hematology Oncology Unknown No outcome recorded
Phase 1/2 NCT00448357 Oct 2005 → Nov 2015 leukemia, myelodysplastic syndrome, myeloproliferative neoplasm, plasma cell neoplasm UNC Lineberger Comprehensive Cancer Center Completed No outcome recorded
Phase 249 trials
Phase 2 NCT07677306 Jul 2026 → Dec 2027 expected myelodysplastic syndrome Peking University People's Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06769568 Jan 2025 → Sep 2028 expected aplastic anemia, disease related to hematopoietic stem cell transplant Institute of Hematology & Blood Diseases Hospital, China Not yet recruiting No outcome recorded
Phase 2 NCT06872333 Nov 2024 → Jun 2030 expected disease related to hematopoietic stem cell transplant, sickle cell disease Masonic Cancer Center, University of Minnesota Recruiting No outcome recorded
Phase 2 NCT06412497 Jun 2024 → May 2035 expected acquired thrombocytopenia, idiopathic aplastic anemia, paroxysmal nocturnal hemoglobinuria, primary acquired red cell aplasia Masonic Cancer Center, University of Minnesota Recruiting No outcome recorded
Phase 2 NCT06066255 Mar 2024 → Mar 2026 hematopoietic and lymphoid cell neoplasm Institut Paoli-Calmettes Unknown No outcome recorded
Phase 2 NCT05293509 Mar 2022 → Sep 2023 disease related to hematopoietic stem cell transplant M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 2 NCT03980769 May 2021 → Jul 2028 expected hematologic disorder Fred Hutchinson Cancer Center Recruiting No outcome recorded
Phase 2 NCT04395222 Oct 2020 → Sep 2022 overdue hematopoietic and lymphoid cell neoplasm Weill Medical College of Cornell University Active not recruiting No outcome recorded
Phase 2 NCT03852407 Feb 2019 → Nov 2033 expected Hodgkins lymphoma, acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia +2 University of Liege Recruiting No outcome recorded
Phase 2 NCT05214066 Feb 2019 → Aug 2022 acute graft versus host disease, chronic graft versus host disease Chinese PLA General Hospital Unknown No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT03793517 Sep 2018 → Oct 2023 overdue acute myeloid leukemia, disease related to hematopoietic stem cell transplant Peking University People's Hospital Recruiting No outcome recorded
Phase 2/3 NCT03631563 Mar 2013 → Dec 2018 graft versus host disease Fujian Medical University Unknown No outcome recorded
Phase 2/3 NCT01019876 Sep 2002 → Sep 2021 Fanconi anemia, bone marrow failure syndrome, osteopetrosis, severe combined immunodeficiency Columbia University Completed No outcome recorded
Phase 310 trials
Phase 3 NCT05385432 Nov 2023 → Dec 2030 expected transplant rejection University Hospital, Tours Recruiting No outcome recorded
Phase 3 NCT01844635 May 2012 → May 2016 acquired aplastic anemia Nagoya University Unknown No outcome recorded
Phase 3 NCT01217723 Apr 2010 → Jan 2014 hematopoietic and lymphoid system neoplasm McMaster University Unknown No outcome recorded
Phase 3 NCT01028092 Mar 2009 → Mar 2014 University Hospital, Brest Completed No outcome recorded
Phase 3 NCT00934557 Mar 2008 → ? Fondazione IRCCS Policlinico San Matteo di Pavia Unknown No outcome recorded
Phase 3 NCT00275509 Jan 2007 → Jun 2010 chronic renal failure syndrome Johns Hopkins University Completed No outcome recorded
Phase 3 NCT00678275 Oct 2006 → Feb 2014 acute lymphoblastic leukemia, acute myeloid leukemia University Medical Center Hamburg-Eppendorf Completed No outcome recorded
Phase 3 NCT00130754 Feb 2005 → Nov 2007 graft versus host disease Hadassah Medical Organization Completed No outcome recorded
Phase 3 NCT00655343 Feb 2003 → Mar 2007 graft versus host disease Neovii Biotech Completed No outcome recorded
Phase 3 NCT00186823 Mar 2002 → Sep 2005 acute lymphoblastic leukemia, acute myeloid leukemia, chronic myeloid leukemia, juvenile myelomonocytic leukemia +2 St. Jude Children's Research Hospital Completed No outcome recorded
Phase 419 trials
Phase 4 NCT05743400 Sep 2023 → Apr 2025 overdue thrombotic microangiopathy Hospices Civils de Lyon Recruiting No outcome recorded
Phase 4 NCT06009965 Jan 2023 → Jan 2025 aplastic anemia Peking Union Medical College Hospital Unknown No outcome recorded
Phase 4 NCT03099122 Aug 2017 → Nov 2019 end stage renal failure Sanofi Completed No outcome recorded
Phase 4 NCT03006419 Dec 2016 → Jul 2019 transplant rejection Coordinación de Investigación en Salud, Mexico Completed No outcome recorded
Phase 4 NCT03088280 Jun 2015 → Jan 2018 Hospital Geral de Fortaleza Unknown No outcome recorded
Phase 4 NCT01856803 Oct 2013 → Jun 2018 graft versus host disease Peking University People's Hospital Completed No outcome recorded
Phase 4 NCT02083991 Jan 2013 → Jan 2017 diabetes mellitus Vastra Gotaland Region Completed No outcome recorded
Phase 4 NCT01729494 Sep 2012 → Dec 2018 University of Cincinnati Completed No outcome recorded
Phase 4 NCT01354301 May 2011 → Apr 2014 cytomegalovirus infection, transplant rejection Hospital do Rim e Hipertensão Completed No outcome recorded
Phase 4 NCT02523768 Jan 2011 → Jan 2020 IgA glomerulonephritis University Hospital of Saint-Etienne Terminated No outcome recorded
Phase not applicable16 trials
NCT05482542 Jan 2023 → Jul 2027 relapsing-remitting multiple sclerosis Scripps Health Withdrawn No outcome recorded
NCT05199103 Jan 2020 → Dec 2023 disease of orbital part of eye adnexa Medical University of Silesia Unknown No outcome recorded
NCT03821987 Dec 2018 → Dec 2021 aplastic anemia, engraftment syndrome Peking University People's Hospital Unknown No outcome recorded
NCT03035422 Jan 2018 → Dec 2021 acute myeloid leukemia Association for Training, Education, and Research in Hematology, Immunology, and Transplantation Completed No outcome recorded
NCT03079089 Jun 2017 → Sep 2023 lymphoid hemopathy Association for Training, Education, and Research in Hematology, Immunology, and Transplantation Completed No outcome recorded
NCT02028416 Sep 2013 → Dec 2017 aplastic anemia National Institute of Blood Disease Center, Pakistan Unknown No outcome recorded
NCT01280617 Oct 2010 → Nov 2013 acute kidney injury Lahey Clinic Completed No outcome recorded
NCT01129323 Nov 2009 → Sep 2011 aplastic anemia City of Hope Medical Center Withdrawn No outcome recorded
NCT00970073 Aug 2009 → Jun 2015 The Cleveland Clinic Completed No outcome recorded
NCT00714480 Jul 2008 → Dec 2009 immunodeficiency disease Swedish Medical Center Completed No outcome recorded
Also used as a comparator or background therapy in 139 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 119 trials
Phase 1 NCT07257419 Background Aug 2026 → Dec 2031 expected childhood acute lymphoblastic leukemia, disease related to hematopoietic stem cell transplant St. Jude Children's Research Hospital Recruiting No outcome recorded
Phase 1 NCT05525507 Background Dec 2022 → Dec 2026 expected chronic transplant rejection, end stage renal failure University of California, Los Angeles Recruiting No outcome recorded
Phase 1 NCT05298358 Background Nov 2022 → Nov 2024 systemic sclerosis Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Terminated No outcome recorded
Phase 1 NCT04521946 Background Jan 2021 → Dec 2022 anaplastic ependymoma, atypical teratoid rhabdoid tumor, central nervous system germ cell tumor, choroid plexus carcinoma +3 M.D. Anderson Cancer Center Withdrawn No outcome recorded
Phase 1 NCT03531736 Background May 2018 → May 2026 overdue myeloid hemopathy Memorial Sloan Kettering Cancer Center Active not recruiting No outcome recorded
Phase 1/210 trials
Phase 1/2 NCT07607197 Background Feb 2024 → May 2027 expected anti-HLA hyperimmunization, end stage renal failure Hospital Universitari Vall d'Hebron Research Institute Recruiting No outcome recorded
Phase 1/2 NCT03597594 Comparator Sep 2021 → Jul 2027 expected severe combined immunodeficiency St. Jude Children's Research Hospital Active not recruiting No outcome recorded
Phase 1/2 NCT04083183 Background Jun 2020 → Jan 2028 expected benign neoplasm Fred Hutchinson Cancer Center Recruiting No outcome recorded
Phase 1/2 NCT04066114 Background Dec 2019 → Sep 2023 disease related to solid organ transplantation National Institute of Allergy and Infectious Diseases (NIAID) Completed No outcome recorded
Phase 1/2 NCT04224558 Background Nov 2019 → Sep 2027 expected Crohn disease Cedars-Sinai Medical Center Recruiting No outcome recorded
Phase 260 trials
Phase 2 NCT07508787 Comparator Jun 2026 → Mar 2028 expected transplant rejection Nefro Avillion Clinical Development, LLC Recruiting No outcome recorded
Phase 2 NCT07570745 Background May 2026 → May 2028 expected acute graft versus host disease Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting No outcome recorded
Phase 2 NCT06646497 Background Jan 2025 → Jan 2030 expected acquired aplastic anemia Assistance Publique - Hôpitaux de Paris Recruiting No outcome recorded
Phase 2 NCT05735717 Background May 2023 → Nov 2027 expected CBL-related disorder, acute lymphoblastic leukemia, acute myeloid leukemia, central nervous system leukemia +6 Masonic Cancer Center, University of Minnesota Recruiting No outcome recorded
Phase 2 NCT05736419 Background Feb 2023 → Feb 2027 expected beta thalassemia, sickle cell disease Memorial Sloan Kettering Cancer Center Recruiting No outcome recorded
Phase 2/33 trials
Phase 2/3 NCT07412470 Background Mar 2026 → Aug 2029 expected transplant rejection Sanofi Recruiting No outcome recorded
Phase 2/3 NCT03799224 Background Dec 2018 → Dec 2021 acute leukemia, disease related to hematopoietic stem cell transplant Peking University People's Hospital Unknown No outcome recorded
Phase 2/3 NCT01087398 Background Sep 2009 → Nov 2012 osteopetrosis Tehran University of Medical Sciences Unknown No outcome recorded
Phase 315 trials
Phase 3 NCT06083129 Comparator Nov 2023 → Nov 2028 expected graft versus host disease Assistance Publique - Hôpitaux de Paris Recruiting No outcome recorded
Phase 3 NCT05457556 Background Mar 2023 → Jun 2026 overdue acute lymphoblastic leukemia, mixed phenotype acute leukemia, myelodysplastic syndrome Children's Oncology Group Active not recruiting No outcome recorded
Phase 3 NCT05600426 Comparator Jan 2023 → Dec 2029 expected aplastic anemia Boston Children's Hospital Active not recruiting No outcome recorded
Phase 3 NCT04547049 Comparator Sep 2020 → Apr 2026 overdue leukemia, myelodysplastic syndrome First Affiliated Hospital of Zhejiang University Active not recruiting No outcome recorded
Phase 3 NCT04302805 Comparator Jul 2020 → Apr 2024 Institute for Clinical and Experimental Medicine Completed No outcome recorded
Phase 427 trials
Phase 4 NCT07203664 Background Oct 2025 → Dec 2026 expected Hospital Universitario La Paz Not yet recruiting No outcome recorded
Phase 4 NCT05634915 Comparator Dec 2022 → Dec 2024 acute leukemia, disease related to hematopoietic stem cell transplant The First Affiliated Hospital of Soochow University Unknown No outcome recorded
Phase 4 NCT04849533 Background Apr 2021 → Jul 2023 transplant rejection University of Cincinnati Unknown No outcome recorded
Phase 4 NCT04009525 Background Jul 2019 → Jul 2023 beta-thalassemia major First Affiliated Hospital of Guangxi Medical University Completed No outcome recorded
Phase 4 NCT03828682 Background Jun 2019 → Jul 2021 immunodeficiency disease Simon Tremblay, PharmD, PhD Unknown No outcome recorded
Phase not applicable5 trials
NCT02936505 Background Oct 2016 → Oct 2025 overdue Vastra Gotaland Region Active not recruiting No outcome recorded
NCT02845596 Comparator Aug 2016 → Nov 2020 acquired aplastic anemia Michael Pulsipher Completed No outcome recorded
NCT01850108 Background May 2013 → Nov 2023 sickle cell disease Vanderbilt-Ingram Cancer Center Unknown No outcome recorded
NCT00859131 Comparator Mar 2009 → Jul 2012 end stage renal failure Medical University of South Carolina Completed No outcome recorded
NCT00709293 Comparator Jul 2008 → May 2009 ischemic disease University of California, Los Angeles Withdrawn No outcome recorded

Evidence & citations 45 cited values

Every value below carries the sentence it was read from. 266 sources stand behind the page.

FieldValueCited text
Known as Thymoglobulin “A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of...” NCT01157949
124

“A prominent example of this class of drugs is Thymoglobulin(TMG), a purified, pasteurized gamma immune globulin, which is obtained by immunization of rabbits with human thymocytes.” NCT00714480

“At our institution, one such antibody preparation (Thymoglobulin) is used in most pediatric heart transplant recipients for 3-5 days immediately after transplantation.” NCT00709293

“Children over two years and adults undergoing a first hematopoietic stem cell transplantation will receiveThymoglobulin® as part of the conditioning.” NCT05743400

“Patients will also receive rabbit antithymocyte globulin (Thymoglobulin) at a dose of 2 mg/kg IV daily for 3 days on transplant days -4, -3, and -2.” NCT01455506

“All patients will start with Thymoglobulin 1 mg/kg before transplant followed by 0,5 mg/kg/d during the next 5 days (total accumulated 3,5 mg/kg).” NCT01195194

“A Pilot, Phase-I Trial of Rabbit Anti-Thymocyte Globulin (rATG, Thymoglobulin™) in Combination With Rapamycin in Relapsed Multiple Myeloma (MM)” NCT00317798

“Two randomized groups of kidney transplant recipients will be each administered the drug Thymoglobulin according to a different dosing regimen.” NCT00906204

“ATG: Thymoglobulin will be administered five times intravenously at 1.5 mg/kg/day from day -11 through day -7 for a total dose of 7.5 mg/kg.” NCT01566656

“The two commonly used ATGs, Thymoglobulin and ATG-F have slightly different antigen profile and antibody concentrations.” PMID 27855166 Nov 2016

“Patients receive immunosuppressive induction treatment with thymoglobulin (at least 1 dose and maximum of 5 doses)” NCT07203664

“rabbit antithymocyte globulin (thymoglobulin, 2.5 mg/kg/d, days -5 to -2; Sanofi, France)” NCT07677306

“Conditioning regimen Thymoglobulin (0.5/mg/kg à D-9, 2 mg /kg at D-8 and 2.5 mg/kg à D-7)” NCT06646497

Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation” NCT01046955

Thymoglobulin (Sangstat), a FDA-approved polyclonal rabbit-IgG antithymocyte preparation” NCT00062712

“Fludarabine IV- Busulfan IV (Busilvex®) - Anti-thymocyte globulines (Thymoglobuline®)” NCT01572181

Thymoglobulin: 2.5 mg /kg/day intravenously (IV) on Days -8 through -5” NCT02776202

Thymoglobulin® (Genzyme) \[rabbit anti-thymocyte globulin (ATG)\]” NCT03292861

“Rabbit antithymocyte globulin (rATG; thymoglobulin, Genzyme)” PMID 22544699 Apr 2012

thymoglobulin (A :rATG ,Sang Stat,France) 2.5mg/kg/dx4d” NCT03821987

“rabbit anti-thymocyte globulin (rATG, Thymoglobulin®)” NCT05385432

“Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®)” NCT03615144

“3 Thymoglobulin doses given prior to thymus tx.” NCT00579709

“ATG (thymoglobulin; Sang Stat, France)” NCT03799224

“ATG (thymoglobulin; Sang Stat, France)” NCT03793517

Thymoglobulin 2 mg/kg IV Days -8, -7” NCT05298358

“rabbit Thymoglobulin (rATG)” NCT07607197

NCT00088543

NCT00887042

NCT04046549

NCT01556347

NCT00040651

NCT00089947

NCT02867800

NCT05735717

NCT04302805

NCT02683291

NCT00476229

NCT00475020

NCT00506948

NCT00737685

NCT00750126

NCT00771745

NCT06872333

NCT01312064

NCT00681343

NCT00806598

NCT00402558

NCT01280617

NCT00542828

NCT00006178

NCT01028092

NCT00592306

NCT02441803

NCT02137239

NCT04888741

NCT01895049

NCT02447822

NCT02512497

NCT00990249

NCT01856803

NCT00685061

NCT01471444

NCT00857389

NCT00669890

NCT00235781

NCT03088280

NCT06066255

NCT00506129

NCT03219359

NCT01354301

NCT03292861

NCT00523809

NCT07052370

NCT02084446

NCT01850108

NCT03852407

NCT02582775

NCT02745717

NCT01157949

NCT00706680

NCT01087398

NCT01622556

NCT00682292

NCT00303667

NCT00593645

NCT00545519

NCT00117689

NCT00916045

NCT03171831

NCT00970073

NCT00899431

NCT00882323

NCT00885833

NCT05743400

NCT02495077

NCT02224872

NCT01246206

NCT02544113

NCT00455013

NCT01135537

NCT00409695

NCT03006419

NCT00813124

NCT02877082

NCT02627573

NCT04903054

NCT02130817

NCT01490723

NCT01844635

NCT00709592

NCT01939171

NCT00679536

NCT00235300

NCT01172418

NCT00275509

NCT00670410

NCT01149993

NCT02464878

NCT06083129

NCT00469014

NCT02083991

NCT01392989

NCT04009525

NCT02833805

Known as anti thymoglobulin “Drug: anti thymoglobulinNCT01856803
Known as anti-human T-lymphocyte immunoglobulin ClinicalTrials.gov intervention name — accepted as the source's own label NCT03357159
Known as Anti-human thymocyte globulin (rabbit) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00007787
Known as Anti-lymphocyte serum Anti-lymphocyte serum (Thymoglobuline) 2.5 mg / kg / day for 2 days (J-3 and J-2)” NCT03079089
Known as Anti-Lymphocyte-Globulin “ATG FRESENIUS (Anti-Lymphocyte-Globulin)” NCT00678275
Known as Anti-T-Lymphocyte Globulin Anti-T-Lymphocyte Globulin (ATG)” NCT00733733
Known as Anti-Thymocyte Globin (ATG) ClinicalTrials.gov intervention name — accepted as the source's own label NCT01106157
Known as Anti-Thymocyte Globulin (Rabbit) “Thymoglobuline (Anti-thymocyte globulin [rabbit]) - Genzyme” NCT00915811
22

Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®)” NCT03615144

“Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)]” NCT00088543

“Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)]” NCT00089947

NCT02790515

NCT03597594

NCT01856257

NCT07257419

NCT03531736

NCT04066114

NCT00564538

NCT00260689

NCT04202835

NCT01790594

NCT01621477

NCT01217723

NCT04224558

NCT02188719

NCT00566696

NCT01810588

NCT04395222

NCT01050764

NCT03600909

Known as anti-thymocyte globulin (rabbit), thymoglobulin anti-thymocyte globulin (rabbit), thymoglobulinNCT00771745
Known as Anti-thymocyte globulines “Fludarabine IV- Busulfan IV (Busilvex®) - Anti-thymocyte globulines (Thymoglobuline®)” NCT01572181
Known as Anti-thymoglobulin, rabbit (ATG, rabbit ATG) ClinicalTrials.gov intervention name — accepted as the source's own label NCT00186628
Known as antithymocyte globulin “reduced intensity preparative regimen that included fludarabine, cyclophosphamide and antithymocyte globulin, allowed engraftment of donor stem cells in subjects with SAA” NCT01129323
7

“Rabbit antithymocyte globulin (rATG, Thymoglobulin®) is the most common induction immunosuppression therapy in kidney transplantation.” PMID 26285695 Aug 2015

“assessing the efficacy and safety of antithymocyte globulin (ATG-Fresenius) plus tacrolimus monotherapy at gradually decreasing doses.” PMID 20883560 Oct 2010

“comparing antithymocyte globulin (Thymoglobulin) (group A, N=43) versus alemtuzumab (group B, N=43) versus daclizumab (group C, N=42)” PMID 24477186 Jun 2014

“Thymoglobulin, rabbit derived antithymocyte globulin (Thymoglobulin, SangStat, Fremont, CA)” NCT00235781

“anti-thymocyte globulin (ATG) will be used to condition the recipients for transplantation” NCT00325741

antithymocyte globulin (Thymoglobulin®, Genzyme; 5 mg/kg total dose)” PMID 36028757 Aug 2022

“Thymoglobulin (anti-thymocyte globulin)” NCT01149993

Known as Antithymocyte Immunoglobulin (Rabbit) ClinicalTrials.gov intervention name — accepted as the source's own label NCT04114188
1

NCT03789006

Known as ATG “We initiated a prospective randomized controlled trial of polyclonal rabbit anti-T-cell globulin (ATG) in patients with type 1 diabetes within 4 weeks of diagnosis and with...” PMID 17491669 Aug 2004
15

“Determine the safety and tolerability, in terms of clinical and laboratory toxicity, of anti-thymocyte globulin (ATG) combined with sirolimus in patients with relapsed multiple myeloma.” NCT00317798

“Transplant recipients received a myeloablative conditioning regimen consisting of total body irradiation, thiotepa, cyclophosphamide, ATG, and OKT3.” NCT00186823

“Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810

“received rabbit anti-thymocyte globulin (ATG) 3 mg/kg on day 8 post-transplant.” PMID 34373186 Aug 2021

“rabbit anti-thymocyte globulin (ATG) (Thymoglobuline, Genzyme)” NCT01844635

“Anti-Thymocyte Globulin (ATG, Thymoglobulin) 4.5 mg/kg IV” NCT04202835

“Fludarabine, Thiotepa, Melphalan, Thymoglobuline (ATG)” NCT00961142

ATG FRESENIUS (Anti-Lymphocyte-Globulin)” NCT00678275

ATG (thymoglobulin; Sang Stat, France)” NCT03799224

“Anti-T-Lymphocyte Globulin (ATG)” NCT00733733

“Thymoglobulin (ATG)” NCT00469014

ATGNCT01490723

NCT02218437

NCT05482542

NCT05634915

Known as ATG (Anti-Thymocyte Globulin) ATG (Anti-Thymocyte Globulin)NCT02188719
Known as ATG (rabbit) “ATG ( rabbit ) 2 mg / kg / d-5” NCT06769568
4

NCT00424489

NCT01104025

NCT00278564

NCT03849651

Known as ATG S Fresenius ATG S FreseniusNCT01810926
Known as ATG-F “Here we reanalyzed and updated a randomized phase 3 trial comparing standard GVHD prophylaxis with or without pretransplantation ATG-Fresenius (ATG-F) in 201 adult patients...” PMID 21467544 Apr 2011
2

“The two commonly used ATGs, Thymoglobulin and ATG-F have slightly different antigen profile and antibody concentrations.” PMID 27855166 Nov 2016

NCT02523768

Known as ATG-Fresenius “The ATG-Fresenius® is administered by slow infusion over four hours after antihistamine (2 bulbs Polaramine® IV) and intravenous methylprednisolone (minimum 30mg); it is...” NCT02523768
14

“Patients who fulfill the inclusion criteria and give their informed consent to participate in the study will be randomized to be treated either with a course of ATG-Fresenius...” NCT00190502

“Patients enrolled in the study will be randomized to receive ATG (Fresenius) at a dosage of either 30 mg/Kg (10 mg/Kg on days -4, -3 and -2) or 15 mg/Kg (5 mg/Kg on days -4, -3 and -2).” NCT00934557

“All patients received rATG for 4 days [ATG-Fresenius (ATG-F) 4 mg/kg/day or Thymoglobulin (Thymo-S) 1.25 mg/kg/day] plus MMF and short-term corticosteroids.” PMID 15814548 May 2005

“assessing the efficacy and safety of antithymocyte globulin (ATG-Fresenius) plus tacrolimus monotherapy at gradually decreasing doses.” PMID 20883560 Oct 2010

“Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810

“treatment with ATG-Fresenius administered in addition to standard treatment” NCT01324934

ATG-Fresenius 20 mg/kg day -4 to -2” NCT01582048

ATG-Fresenius versus ATG” NCT03631563

NCT00934557

NCT02028416

NCT00678275

NCT02377193

NCT00861536

NCT00733733

Known as ATG-Fresenius S “The purpose of this study is to assess the efficacy and safety of the study drug, known as "ATG Fresenius S," which is sometimes called "EZ-2053," to prevent a lung transplant...” NCT00105183
3

“anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159

NCT01324934

NCT00655343

Known as ATLG “Although rabbit anti-T-lymphocyte globulin (ATLG) is largely used for the prevention of immune-mediated complications” PMID 28705454 Jul 2017
1

“anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159

Known as EZ-2053 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00105183
Known as Grafalon “anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159
Known as IMTIX-Sangstat ATG “Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810