Thymoglobulin
Trials 113 · started per year
Also used as a comparator or background therapy in 139 trials
Evidence & citations 45 cited values
Every value below carries the sentence it was read from. 266 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Thymoglobulin | “A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of...” NCT01157949 ↗124“A prominent example of this class of drugs is Thymoglobulin(TMG), a purified, pasteurized gamma immune globulin, which is obtained by immunization of rabbits with human thymocytes.” NCT00714480 ↗ “At our institution, one such antibody preparation (Thymoglobulin) is used in most pediatric heart transplant recipients for 3-5 days immediately after transplantation.” NCT00709293 ↗ “Children over two years and adults undergoing a first hematopoietic stem cell transplantation will receiveThymoglobulin® as part of the conditioning.” NCT05743400 ↗ “Patients will also receive rabbit antithymocyte globulin (Thymoglobulin) at a dose of 2 mg/kg IV daily for 3 days on transplant days -4, -3, and -2.” NCT01455506 ↗ “All patients will start with Thymoglobulin 1 mg/kg before transplant followed by 0,5 mg/kg/d during the next 5 days (total accumulated 3,5 mg/kg).” NCT01195194 ↗ “A Pilot, Phase-I Trial of Rabbit Anti-Thymocyte Globulin (rATG, Thymoglobulin™) in Combination With Rapamycin in Relapsed Multiple Myeloma (MM)” NCT00317798 ↗ “Two randomized groups of kidney transplant recipients will be each administered the drug Thymoglobulin according to a different dosing regimen.” NCT00906204 ↗ “ATG: Thymoglobulin will be administered five times intravenously at 1.5 mg/kg/day from day -11 through day -7 for a total dose of 7.5 mg/kg.” NCT01566656 ↗ “The two commonly used ATGs, Thymoglobulin and ATG-F have slightly different antigen profile and antibody concentrations.” PMID 27855166 ↗ Nov 2016 “Patients receive immunosuppressive induction treatment with thymoglobulin (at least 1 dose and maximum of 5 doses)” NCT07203664 ↗ “rabbit antithymocyte globulin (thymoglobulin, 2.5 mg/kg/d, days -5 to -2; Sanofi, France)” NCT07677306 ↗ “Conditioning regimen Thymoglobulin (0.5/mg/kg à D-9, 2 mg /kg at D-8 and 2.5 mg/kg à D-7)” NCT06646497 ↗ “Thymoglobulin Versus Alemtuzumab Versus Daclizumab in Living Donor Renal Transplantation” NCT01046955 ↗ “Thymoglobulin (Sangstat), a FDA-approved polyclonal rabbit-IgG antithymocyte preparation” NCT00062712 ↗ “Fludarabine IV- Busulfan IV (Busilvex®) - Anti-thymocyte globulines (Thymoglobuline®)” NCT01572181 ↗ “Thymoglobulin: 2.5 mg /kg/day intravenously (IV) on Days -8 through -5” NCT02776202 ↗ “Thymoglobulin® (Genzyme) \[rabbit anti-thymocyte globulin (ATG)\]” NCT03292861 ↗ “Rabbit antithymocyte globulin (rATG; thymoglobulin, Genzyme)” PMID 22544699 ↗ Apr 2012 “thymoglobulin (A :rATG ,Sang Stat,France) 2.5mg/kg/dx4d” NCT03821987 ↗ “rabbit anti-thymocyte globulin (rATG, Thymoglobulin®)” NCT05385432 ↗ “Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®)” NCT03615144 ↗ “3 Thymoglobulin doses given prior to thymus tx.” NCT00579709 ↗ “ATG (thymoglobulin; Sang Stat, France)” NCT03799224 ↗ “ATG (thymoglobulin; Sang Stat, France)” NCT03793517 ↗ “Thymoglobulin 2 mg/kg IV Days -8, -7” NCT05298358 ↗ “rabbit Thymoglobulin (rATG)” NCT07607197 ↗ |
| Known as | anti thymoglobulin | “Drug: anti thymoglobulin” NCT01856803 ↗ |
| Known as | anti-human T-lymphocyte immunoglobulin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03357159 ↗ |
| Known as | Anti-human thymocyte globulin (rabbit) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00007787 ↗ |
| Known as | Anti-lymphocyte serum | “Anti-lymphocyte serum (Thymoglobuline) 2.5 mg / kg / day for 2 days (J-3 and J-2)” NCT03079089 ↗ |
| Known as | Anti-Lymphocyte-Globulin | “ATG FRESENIUS (Anti-Lymphocyte-Globulin)” NCT00678275 ↗ |
| Known as | Anti-T-Lymphocyte Globulin | “Anti-T-Lymphocyte Globulin (ATG)” NCT00733733 ↗ |
| Known as | Anti-Thymocyte Globin (ATG) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT01106157 ↗ |
| Known as | Anti-Thymocyte Globulin (Rabbit) | “Thymoglobuline (Anti-thymocyte globulin [rabbit]) - Genzyme” NCT00915811 ↗22“Anti-Thymocyte Globulin (Rabbit) (Thymoglobulin®)” NCT03615144 ↗ “Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)]” NCT00088543 ↗ “Thymoglobulin [Anti-Thymocyte Globulin (Rabbit)]” NCT00089947 ↗ |
| Known as | anti-thymocyte globulin (rabbit), thymoglobulin | “anti-thymocyte globulin (rabbit), thymoglobulin” NCT00771745 ↗ |
| Known as | Anti-thymocyte globulines | “Fludarabine IV- Busulfan IV (Busilvex®) - Anti-thymocyte globulines (Thymoglobuline®)” NCT01572181 ↗ |
| Known as | Anti-thymoglobulin, rabbit (ATG, rabbit ATG) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00186628 ↗ |
| Known as | antithymocyte globulin | “reduced intensity preparative regimen that included fludarabine, cyclophosphamide and antithymocyte globulin, allowed engraftment of donor stem cells in subjects with SAA” NCT01129323 ↗7“Rabbit antithymocyte globulin (rATG, Thymoglobulin®) is the most common induction immunosuppression therapy in kidney transplantation.” PMID 26285695 ↗ Aug 2015 “assessing the efficacy and safety of antithymocyte globulin (ATG-Fresenius) plus tacrolimus monotherapy at gradually decreasing doses.” PMID 20883560 ↗ Oct 2010 “comparing antithymocyte globulin (Thymoglobulin) (group A, N=43) versus alemtuzumab (group B, N=43) versus daclizumab (group C, N=42)” PMID 24477186 ↗ Jun 2014 “Thymoglobulin, rabbit derived antithymocyte globulin (Thymoglobulin, SangStat, Fremont, CA)” NCT00235781 ↗ “anti-thymocyte globulin (ATG) will be used to condition the recipients for transplantation” NCT00325741 ↗ “antithymocyte globulin (Thymoglobulin®, Genzyme; 5 mg/kg total dose)” PMID 36028757 ↗ Aug 2022 “Thymoglobulin (anti-thymocyte globulin)” NCT01149993 ↗ |
| Known as | Antithymocyte Immunoglobulin (Rabbit) | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04114188 ↗ |
| Known as | ATG | “We initiated a prospective randomized controlled trial of polyclonal rabbit anti-T-cell globulin (ATG) in patients with type 1 diabetes within 4 weeks of diagnosis and with...” PMID 17491669 ↗ Aug 200415“Determine the safety and tolerability, in terms of clinical and laboratory toxicity, of anti-thymocyte globulin (ATG) combined with sirolimus in patients with relapsed multiple myeloma.” NCT00317798 ↗ “Transplant recipients received a myeloablative conditioning regimen consisting of total body irradiation, thiotepa, cyclophosphamide, ATG, and OKT3.” NCT00186823 ↗ “Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810 ↗ “received rabbit anti-thymocyte globulin (ATG) 3 mg/kg on day 8 post-transplant.” PMID 34373186 ↗ Aug 2021 “rabbit anti-thymocyte globulin (ATG) (Thymoglobuline, Genzyme)” NCT01844635 ↗ “Anti-Thymocyte Globulin (ATG, Thymoglobulin) 4.5 mg/kg IV” NCT04202835 ↗ “Fludarabine, Thiotepa, Melphalan, Thymoglobuline (ATG)” NCT00961142 ↗ “ATG FRESENIUS (Anti-Lymphocyte-Globulin)” NCT00678275 ↗ “ATG (thymoglobulin; Sang Stat, France)” NCT03799224 ↗ “Anti-T-Lymphocyte Globulin (ATG)” NCT00733733 ↗ “Thymoglobulin (ATG)” NCT00469014 ↗ “ATG” NCT01490723 ↗ |
| Known as | ATG (Anti-Thymocyte Globulin) | “ATG (Anti-Thymocyte Globulin)” NCT02188719 ↗ |
| Known as | ATG (rabbit) | “ATG ( rabbit ) 2 mg / kg / d-5” NCT06769568 ↗ |
| Known as | ATG S Fresenius | “ATG S Fresenius” NCT01810926 ↗ |
| Known as | ATG-F | “Here we reanalyzed and updated a randomized phase 3 trial comparing standard GVHD prophylaxis with or without pretransplantation ATG-Fresenius (ATG-F) in 201 adult patients...” PMID 21467544 ↗ Apr 20112“The two commonly used ATGs, Thymoglobulin and ATG-F have slightly different antigen profile and antibody concentrations.” PMID 27855166 ↗ Nov 2016 |
| Known as | ATG-Fresenius | “The ATG-Fresenius® is administered by slow infusion over four hours after antihistamine (2 bulbs Polaramine® IV) and intravenous methylprednisolone (minimum 30mg); it is...” NCT02523768 ↗14“Patients who fulfill the inclusion criteria and give their informed consent to participate in the study will be randomized to be treated either with a course of ATG-Fresenius...” NCT00190502 ↗ “Patients enrolled in the study will be randomized to receive ATG (Fresenius) at a dosage of either 30 mg/Kg (10 mg/Kg on days -4, -3 and -2) or 15 mg/Kg (5 mg/Kg on days -4, -3 and -2).” NCT00934557 ↗ “All patients received rATG for 4 days [ATG-Fresenius (ATG-F) 4 mg/kg/day or Thymoglobulin (Thymo-S) 1.25 mg/kg/day] plus MMF and short-term corticosteroids.” PMID 15814548 ↗ May 2005 “assessing the efficacy and safety of antithymocyte globulin (ATG-Fresenius) plus tacrolimus monotherapy at gradually decreasing doses.” PMID 20883560 ↗ Oct 2010 “Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810 ↗ “treatment with ATG-Fresenius administered in addition to standard treatment” NCT01324934 ↗ “ATG-Fresenius 20 mg/kg day -4 to -2” NCT01582048 ↗ “ATG-Fresenius versus ATG” NCT03631563 ↗ |
| Known as | ATG-Fresenius S | “The purpose of this study is to assess the efficacy and safety of the study drug, known as "ATG Fresenius S," which is sometimes called "EZ-2053," to prevent a lung transplant...” NCT00105183 ↗3“anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159 ↗ |
| Known as | ATLG | “Although rabbit anti-T-lymphocyte globulin (ATLG) is largely used for the prevention of immune-mediated complications” PMID 28705454 ↗ Jul 20171“anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159 ↗ |
| Known as | EZ-2053 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00105183 ↗ |
| Known as | Grafalon | “anti-human T-lymphocyte immunoglobulin (ATLG, Grafalon®, formerly ATG-Fresenius S, Neovii Pharmaceuticals)” NCT03357159 ↗ |
| Known as | IMTIX-Sangstat ATG | “Single shot of a polyclonal antilymphocyte preparation (ATG-Fresenius - 8 mg/kg, or IMTIX-Sangstat ATG 4 mg/kg/day).” NCT00316810 ↗ |
| Known as | Lapine T-Lymphocyte Immune Globulin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04521946 ↗ |
| Known as | Rabbit Anti-Human T-Lymphocyte Globulin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT03828682 ↗ |
| Known as | Rabbit Anti-Human Thymocyte Globulin | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00316810 ↗ |
| Known as | rabbit anti-T-lymphocyte globulin | “Although rabbit anti-T-lymphocyte globulin (ATLG) is largely used for the prevention of immune-mediated complications” PMID 28705454 ↗ Jul 2017 |
| Known as | Rabbit Anti-thymocyte globulin (ATG) | “Thymoglobulin® (Genzyme) \[rabbit anti-thymocyte globulin (ATG)\]” NCT03292861 ↗ |
| Known as | Rabbit Anti-thymocyte Globulin (rATG) | “Thymoglobulin®, Rabbit Anti-thymocyte Globulin (rATG)” NCT00542828 ↗ |
| Known as | rabbit anti-thymocyte immunoglobulin | “rabbit anti-thymocyte immunoglobulin (r-ATG) 3 mg/kg/d x 5 days” NCT06009965 ↗ |
| Known as | rabbit antithymocyte globulin | “A Non-randomized, Phase II Study of Eltrombopag in Combination With Rabbit Anti-thymocyte Globulin/Cyclosporine A (ATG/CsA) in Subjects With Moderate or More Severe Aplastic...” NCT02404025 ↗53“In mesenchymal stem cells (MSC) group, UC-MSCs were injected intravenously at a dose of 1 × 106/kg per week starting on the 14th day after administration of rabbit...” PMID 33639900 ↗ Feb 2021 “Rabbit anti-thymocyte globulin (rATG), a polyclonal rabbit-derived antibody that depletes lymphocytes, including T cells, was introduced to prevent GVHD and transplant rejection.” NCT05634915 ↗ “Describe the pharmacokinetics of rabbit anti-thymocyte globulin (rATG) in patients receiving allogeneic transplantation and determine the frequency of rATG antibody development” NCT00186823 ↗ “Different outcomes between cyclophosphamide plus horse or rabbit antithymocyte globulin for HLA-identical sibling bone marrow transplant in severe aplastic anemia.” PMID 22796534 ↗ Jul 2012 “Patients will also receive rabbit antithymocyte globulin (Thymoglobulin) at a dose of 2 mg/kg IV daily for 3 days on transplant days -4, -3, and -2.” NCT01455506 ↗ “A Pilot, Phase-I Trial of Rabbit Anti-Thymocyte Globulin (rATG, Thymoglobulin™) in Combination With Rapamycin in Relapsed Multiple Myeloma (MM)” NCT00317798 ↗ “Patients will receive Thiotepa on Days -5, -4, Cyclophosphamide on Days -3, -2 and rabbit antithymocyte globulin on Days -4, -3, -2 and -1.” NCT01049854 ↗ “Rabbit antithymocyte globulin (rATG, Thymoglobulin®) is the most common induction immunosuppression therapy in kidney transplantation.” PMID 26285695 ↗ Aug 2015 “Our previous case report has shown promising results for rabbit antithymocyte globulin (rATG) in the treatment of Graves' orbitopathy.” PMID 35615718 ↗ May 2022 “All subjects received induction therapy with basiliximab or rabbit anti-thymocyte globulin, in the peritransplant period.” NCT01950819 ↗ “Thymoglobulin (rabbit antithymocyte globulin) is FDA approved for the treatment of acute cellular rejection.” NCT01280617 ↗ “The patients also receive rabbit Antithymocyte Globulin (rATG), tacrolimus, and sirolimus.” NCT02166177 ↗ “rabbit antithymocyte globulin (thymoglobulin, 2.5 mg/kg/d, days -5 to -2; Sanofi, France)” NCT07677306 ↗ “All subjects pre-transplant days -5,-4,-3: 3 doses 2mg/kg rabbit anti-thymocyte globulin.” NCT00849888 ↗ “received rabbit anti-thymocyte globulin (ATG) 3 mg/kg on day 8 post-transplant.” PMID 34373186 ↗ Aug 2021 “induction therapy with rabbit antithymocyte globulin (RATG, Thymoglobulin®)” NCT01517984 ↗ “Cyclophosphamide (200 mg /kg) / rabbit antithymocyte globulin (6.0 mg/kg)” NCT05482542 ↗ “rabbit antithymocyte globulin (2 × 1.5 mg/kg, postoperative days 0 and 1)” PMID 37525369 ↗ Aug 2023 “rabbit anti-thymocyte globulin (ATG) (Thymoglobuline, Genzyme)” NCT01844635 ↗ “rabbit anti-thymocyte globulin (rATG, Thymoglobulin®)” NCT05385432 ↗ “rabbit anti-thymocyte globulin (rATG)” NCT05525507 ↗ “Rabbit Anti-thymocyte globulin (ATG)” NCT01565616 ↗ |
| Known as | rabbit Thymoglobulin (r-ATG) | “rabbit Thymoglobulin (r-ATG)” NCT02084446 ↗ |
| Known as | rabbitATG | “The patient will also receive Thymoglobulin (rabbitATG) on Day -4 to Day -2.” NCT00679536 ↗21“Patients will receive rabbit ATG 2.5 mg/kg on Day -2 and -1 (total 5 mg/kg)” NCT07570745 ↗ “rabbit ATG at 1.5 mg/kg i.v. on days -11 through -7 pretransplantation” NCT00325741 ↗ “alemtuzumab will be replaced with rabbit ATG on days -10 through -7” NCT02165007 ↗ “rabbit ATG (2.0 mg/kg/day) day -5,-4,-3, and -2” NCT01461837 ↗ |
| Known as | rATG | “Within 3 weeks of the apheresis stem cell collection, the first group's participants will be admitted to the hospital and will undergo a five-day conditioning regimen...” NCT00230035 ↗19“All patients received either rabbit antithymocyte globulin (rATG) or interleukin 2 receptor antagonists (IL-2RA) in addition to tacrolimus (FK), mycophenolate mofetil (MMF),...” PMID 25557762 ↗ Jan 2015 “Rabbit anti-thymocyte globulin (rATG), a polyclonal rabbit-derived antibody that depletes lymphocytes, including T cells, was introduced to prevent GVHD and transplant rejection.” NCT05634915 ↗ “Describe the pharmacokinetics of rabbit anti-thymocyte globulin (rATG) in patients receiving allogeneic transplantation and determine the frequency of rATG antibody development” NCT00186823 ↗ “The first investigational conditioning regimen is cyclophosphamide (chemotherapy) and rATG (rabbit anti-thymocyte globulin, a protein against immune cells).” NCT05482542 ↗ “A Pilot, Phase-I Trial of Rabbit Anti-Thymocyte Globulin (rATG, Thymoglobulin™) in Combination With Rapamycin in Relapsed Multiple Myeloma (MM)” NCT00317798 ↗ “HPSC infusion will be preceded by a conditioning regimen of total lymphoid irradiation (TLI) and rabbit anti-thymocyte globulin (rATG).” NCT05525507 ↗ “Rabbit antithymocyte globulin (rATG, Thymoglobulin®) is the most common induction immunosuppression therapy in kidney transplantation.” PMID 26285695 ↗ Aug 2015 “Our previous case report has shown promising results for rabbit antithymocyte globulin (rATG) in the treatment of Graves' orbitopathy.” PMID 35615718 ↗ May 2022 “The patients also receive rabbit Antithymocyte Globulin (rATG), tacrolimus, and sirolimus.” NCT02166177 ↗ “rabbit anti-thymocyte immunoglobulin (r-ATG) 3 mg/kg/d x 5 days” NCT06009965 ↗ “Fludarabine-Melphalan & Rabbit antithymocyte globulin (r-ATG)” NCT00943800 ↗ “Rabbit antithymocyte globulin (rATG; thymoglobulin, Genzyme)” PMID 22544699 ↗ Apr 2012 “organ perfusion with rabbit anti-thymocyte globulin (rATG)” NCT03377283 ↗ “Induction therapy: rabbit anti-thymocyte globulin (rATG)” NCT03663335 ↗ “thymoglobulin (A :rATG ,Sang Stat,France) 2.5mg/kg/dx4d” NCT03821987 ↗ “rabbit anti-thymocyte globulin (rATG, Thymoglobulin®)” NCT05385432 ↗ “rATG 1.5 mg/kg/dose IV is given from day -4 to -1.” NCT01129323 ↗ “r-ATG (Anti-thymocyte globulin (rabbit))” NCT00260689 ↗ “rabbit Thymoglobulin (rATG)” NCT07607197 ↗ |
| Known as | rATG (rabbit antithymocyte globulin) | “rATG (rabbit antithymocyte globulin)” NCT01172418 ↗ |
| Known as | Sang Stat | “thymoglobulin (A :rATG ,Sang Stat,France) 2.5mg/kg/dx4d” NCT03821987 ↗ |
| Known as | Thymo-S | “All patients received rATG for 4 days [ATG-Fresenius (ATG-F) 4 mg/kg/day or Thymoglobulin (Thymo-S) 1.25 mg/kg/day] plus MMF and short-term corticosteroids.” PMID 15814548 ↗ May 2005 |
| Known as | Thymoglobulin, Genzyme | “Thymoglobulin, Genzyme” NCT00682292 ↗ |
| Known as | Thymoglobuline | “Thymoglobuline 3 mg/kg in N/S 500-800 mL (less than 0.5 mg/mL) or lymphoglobuline 15 mg/kg in N/S 500-800 mL (less than 2 mg/mL) iv daily at 8 am on days -4 to -2.” NCT01145976 ↗13“Thymoglobuline 3 mg/kg in N/S 500-800 mL (less than 0.5 mg/mL) or lymphoglobuline 15 mg/kg in N/S 500-800 mL (less than 2 mg/mL) iv daily at 8 am on days -4 to -2.” NCT00774527 ↗ “Flu-Bu-ATG (Study A) associated Fludarabine (30mg/m²/5 days), Oral Busulfan (8 mg/kg over 2 days) and Thymoglobuline (2.5 mg/m²/1day).” NCT00894049 ↗ “ATG (Thymoglobuline, rabbit) was used as 1 mg/kg/d from day -5 to day -3 and 2 mg/kg/d on day -2.” NCT05214066 ↗ “associating Fludarabine, Thymoglobuline, and intravenous Busulfan with adapted dose” NCT02483325 ↗ “Anti-lymphocyte serum (Thymoglobuline) 2.5 mg / kg / day for 2 days (J-3 and J-2)” NCT03035422 ↗ “Anti-lymphocyte serum (Thymoglobuline) 2.5 mg / kg / day for 2 days (J-3 and J-2)” NCT03079089 ↗ “rabbit anti-thymocyte globulin (ATG) (Thymoglobuline, Genzyme)” NCT01844635 ↗ “rabbit antithymocyte globulin (ATG, Thymoglobuline®)” NCT01530555 ↗ |
| Known as | TMG | “A prominent example of this class of drugs is Thymoglobulin(TMG), a purified, pasteurized gamma immune globulin, which is obtained by immunization of rabbits with human thymocytes.” NCT00714480 ↗ |
| Action | Deplete | “thymoglobulin to kill the T-cells” NCT00040651 ↗ |
| Modality | Protein / enzyme biologic | “a FDA-approved polyclonal rabbit-IgG antithymocyte preparation” NCT00006178 ↗ |
| Route | Intravenous | “Thymoglobulin will be given intravenously” NCT00006178 ↗ |