drugset / Trial / NCT00475020

Allogeneic Stem Cell Transplantation for Myelofibrosis and Myelodysplastic Syndrome

NCT00475020

Phase 2 Completed 63 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to learn if using a combination of fludarabine, busulfan, and antithymocyte globulin (ATG) can help to control myelofibrosis or myelodysplastic syndrome in patients receiving a bone marrow or blood stem cell transplant. The safety of these drugs will also be studied.

Timeline

Start
2006-01-04
Primary completion
2017-10-04
Completion
2017-10-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Busulfan Small molecule 100 mg/m2 Intravenous
Subject Fludarabine Small molecule 40 mg/m2 Intravenous
Subject Thymoglobulin Protein / enzyme biologic 2.5 mg/kg Intravenous

Indications