drugset / Trial / NCT00750126
Allogeneic Hematopoietic Stem Cell Transplantation
Non-randomizedSingle-groupOpen-labelTreatment
Summary
To assess the engraftment of hematopoietic stem cells following reduced-intensity conditioning in children presenting with solid tumors or hematological malignancy by evaluating post-transplantation chimerism and hematological reconstitution. To study acute and/or chronic graft-versus-host reaction (incidence and severity) and immune reconstitution, post-transplantation To study the effectiveness of the protocol on tumor response. To study overall survival.
Timeline
- Start
- 2007-04
- Primary completion
- 2009-04
- Completion
- 2009-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Busulfan | Small molecule | — | — |
| Subject | Fludarabine | Small molecule | — | — |
| Subject | Thymoglobulin | Protein / enzyme biologic | — | — |