drugset / Trial / NCT00726739

Aldesleukin With or Without Vaccine Therapy in Treating Patients With Stage IV Melanoma

NCT00726739 ↗

Phase 2 Completed 21 enrolled Masonic Cancer Center, University of Minnesota
RandomizedCrossoverOpen-labelTreatment

Summary

RATIONALE: Aldesleukin may stimulate the white blood cells to kill tumor cells. Vaccines may help the body build an effective immune response to kill tumor cells. Giving aldesleukin together with vaccine therapy may kill more tumor cells. It is not yet known whether aldesleukin is more effective with or without vaccine therapy in treating melanoma. PURPOSE: This randomized phase II trial is studying how well aldesleukin works when given with or without vaccine therapy in treating patients with stage IV melanoma.

Timeline

Start
2008-06
Primary completion
2011-06
Completion
2011-06

Drugs

EvaluationDrugModalityDoseRoute
Subject LP2307 Vaccine 0.2 ml Other
Subject aldesleukin Protein / enzyme biologic 1e+07 iu Subcutaneous

Indications