drugset / Trial / NCT00726999
Perioperative Use of Gabapentin To Decrease Narcotic Requirements in Spinal Fusion
Completed
63 enrolled
Medical College of Wisconsin
Children's Hospital and Health System Foundation, Wisconsin · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Blinded study using oral gabapentin in load pre-operative (15mg/kg) and maintenance 5mg/kg three times a day (TID) for 5 days or discharge, Patient Controlled Analgesia (PCA) morphine and placebo group with similar pills, also PCA morphine. The goal is to measure morphine usage and incidence of morphine side effects (pruritis, days foley, days to first stool, sedation, pain scores, PCA use).
Timeline
- Start
- 2006-06
- Primary completion
- 2008-07
- Completion
- 2009-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gabapentin | Small molecule | 5 mg/kg | Oral |
| Comparator | Morphine | Other / unclassified | — | — |
Indications
No indication recorded.