drugset / Trial / NCT00738062

Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)

NCT00738062

Phase 3 Completed 103 enrolled Chelsea Therapeutics
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to assess the durability of effect of Droxidopa in treating symptoms of neurogenic orthostatic hypotension in patients with Primary Autonomic Failure (Pure Autonomic Failure, Multiple System Atrophy, Parkinson's Disease), Non-diabetic neuropathy, or Beta Hydroxylase deficiency.

Timeline

Start
2008-01
Primary completion
2010-12
Completion
2010-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Droxidopa Small molecule 100 mg Oral
Comparator Droxidopa Small molecule 200 mg Oral
Comparator Droxidopa Small molecule 300 mg Oral
Comparator Droxidopa Small molecule 400 mg Oral
Comparator Droxidopa Small molecule 500 mg Oral
Comparator Droxidopa Small molecule 600 mg Oral