drugset / Trial / NCT00738699

An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer

NCT00738699 ↗

Phase 2 Terminated 415 enrolled Morphotek
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study is being conducted to find out if paclitaxel works better when given together with an experimental drug called MORAb-003 (farletuzumab) or alone in patients with platinum-resistant or refractory relapsed ovarian cancer

Timeline

Start
2008-09
Primary completion
2011-12
Completion
2012-01

Outcome

Outcome not reported

Stopped: “study did not meet pre-specified criteria for continuation following interim futility analysis”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Farletuzumab Monoclonal antibody 2.5 mg/kg Intravenous
Comparator Paclitaxel Small molecule 80 mg/m2 Intravenous

Indications