drugset / Trial / NCT00743028

Assess the Oral Bioavailability of New ABT-263 Formulations

NCT00743028

Phase 1 Completed 36 enrolled Abbott Genentech, Inc. · collab
RandomizedCrossoverOpen-labelTreatment

Summary

This is a randomized, open-label, multicenter crossover study to determine the oral bioavailability of new ABT-263 formulations relative to that of the current ABT-263 formulation being administered in ongoing Phase 1/2a studies. Approximately 36 evaluable subjects with lymphoid malignancies, including chronic lymphocytic leukemia, and solid tumors will be enrolled in this study.

Timeline

Start
2008-08
Primary completion
2010-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Navitoclax Small molecule