drugset

drugset / Trial / NCT00743444

TLESR-impedance Study in Patients

NCT00743444 ↗

Phase 2 Completed 27 enrolled AstraZeneca

RandomizedCrossoverQuadruple-blindBasic science

Summary

The purpose of the study is to compare frequency and content of reflux episodes in patients with gastroesophageal reflux disease.

Timeline

Start: 2007-02
Primary completion: 2008-02
Completion: 2008-02

Publications

Boeckxstaens GE, Beaumont H, Mertens V, Denison H, Ruth M, Adler J, Silberg DG, Sifrim D. Effects of lesogaberan on reflux and lower esophageal sphincter function in patients with gastroesophageal reflux disease. Gastroenterology. 2010 Aug;139(2):409-17. doi: 10.1053/j.gastro.2010.04.051. Epub 2010 May 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	lesogaberan	Small molecule	65 mg	Oral

Indications