drugset / Trial / NCT00743587
A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The Thumb
RandomizedCrossoverDouble-blindOther
Summary
The purpose of this study is to determine if the measurement of pressure pain thresholds, in patients suffering osteoarthritis of the thumb, can be used to assess the activity of potential analgesic agents after a single dose. The study will use agents known to give pain relief in osteoarthritis as positive controls. These agents are: tramadol, naproxen and oxycodone.
Timeline
- Start
- 2008-09
- Primary completion
- 2009-03
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Naproxen | Small molecule | 500 mg | Oral |
| Comparator | Oxycodone | Other / unclassified | 20 mg | Oral |
| Comparator | Tramadol | Other / unclassified | 100 mg | Oral |