drugset / Trial / NCT00743678

Neoadjuvant FOLFOX6 + Cetuximab in Patients With Colorectal Cancer and Unresectable Liver Metastasis

NCT00743678 ↗

Phase 2 Completed 73 enrolled Samsung Medical Center
Non-randomizedSingle-groupOpen-labelTreatment

Summary

An innovative therapeutic strategy to increase the complete resection rate is of utmost importance in order to enhance survival in colorectal cancer patients with unresectable liver-only metastasis. Therefore, the investigators propose a prospective study of neoadjuvant chemotherapy using FOLFOX6 plus cetuximab to convert initially unresectable liver metastasis to potentially resectable disease.

Timeline

Start
2008-06
Primary completion
2012-01
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Cetuximab Monoclonal antibody — —

Indications