drugset / Trial / NCT00750425
Phase 1 Study of the Effect of Ketoconazole on the PK of Multiple Doses of Cediranib in Patients With Solid Tumours
NaSingle-groupOpen-labelTreatment
Summary
Phase I, open study to assess the effect of ketoconazole, a marketed drug, on the way the body handles the experimental drug cediranib, in patients with advanced cancer.
Timeline
- Start
- 2008-08
- Primary completion
- 2009-04
- Completion
- 2011-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cediranib | Small molecule | 20 mg | Oral |
| Subject | Cediranib | Small molecule | 30 mg | Oral |
| Subject | Cediranib | Small molecule | 45 mg | Oral |
| Subject | Ketoconazole | Small molecule | 400 mg | — |