Phase 1 29 trials
Phase 1
NCT01364051
May 2011 → Jun 2019 overdue
cutaneous melanoma , metastatic melanoma , refractory malignant neoplasm
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1
NCT01160926
Jul 2010 → Oct 2013
rectal carcinoma
The Christie NHS Foundation Trust
Terminated
No outcome recorded
Phase 1
NCT01131234
May 2010 → Sep 2014
adult anaplastic ependymoma , adult brainstem glioma , adult glioblastoma , anaplastic astrocytoma +15
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00979862
Mar 2010 → May 2012
adult glioblastoma , giant cell glioblastoma , gliosarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT01065662
Feb 2010 → Sep 2013
cervical cancer , endometrial cancer , fallopian tube cancer , ovarian cancer +1
Susana M. Campos, MD
Completed
No outcome recorded
Phase 1
NCT00981721
Sep 2009 → May 2010
high grade malignant neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00937482
Aug 2009 → Mar 2011
male breast carcinoma , malignant colon neoplasm , melanoma , metastatic malignant neoplasm in the brain +3
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 1
NCT00960349
Aug 2009 → Jan 2010
gastric cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00750841
Sep 2008 → Jul 2009 overdue
cancer
AstraZeneca
Active not recruiting
No outcome recorded
Phase 1
NCT00750425
Aug 2008 → Apr 2009
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00748891
Aug 2008 → Feb 2010
cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00621361
Feb 2008 → Aug 2009
lung cancer
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00621725
Jan 2008 → Jul 2010
cancer of unknown primary site
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00539331
Sep 2007 → Sep 2008
non-small cell lung carcinoma
AstraZeneca
Terminated
No outcome recorded
Phase 1
NCT00503204
Sep 2007 → Dec 2008
brain neoplasm , glioblastoma
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00458731
May 2007 → Dec 2013
Burkitt lymphoma , Hodgkins lymphoma , MALT lymphoma , T-cell large granular lymphocyte leukemia +19
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00475956
May 2007 → Oct 2008
neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00321581
May 2006 → Oct 2011
acute myeloid leukemia , refractory malignant neoplasm
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00326664
Mar 2006 → Jul 2015
atypical teratoid rhabdoid tumor , cerebellar astrocytoma , childhood brain meningioma , childhood brain stem glioma +13
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1
NCT00243347
Dec 2005 → May 2008
head and neck neoplasm , non-small cell lung carcinoma
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00343408
Nov 2005 → Sep 2007
colorectal cancer , lung cancer
NCIC Clinical Trials Group
Completed
No outcome recorded
Phase 1
NCT00503412
Nov 2005 → May 2006
metastatic malignant neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00503477
Oct 2005 → Jul 2007
neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00107250
Jan 2005 → Oct 2009
colorectal cancer , lung cancer
NCIC Clinical Trials Group
Completed
No outcome recorded
Phase 1
NCT00502567
Jan 2005 → Nov 2007
—
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00502060
Aug 2004 → Jun 2006
—
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00502385
Apr 2004 → ?
myeloid leukemia
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00502164
Mar 2004 → ?
prostate adenocarcinoma
AstraZeneca
Completed
No outcome recorded
Phase 1
NCT00501605
Feb 2003 → Apr 2005
neoplasm
AstraZeneca
Completed
No outcome recorded
Show 19 more trials
Phase 1/2 5 trials
Phase 1/2
NCT02484404
Jun 2015 → Oct 2027 expected
breast cancer , colorectal cancer
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1/2
NCT01208051
Sep 2010 → Feb 2020
thyroid Hurthle cell carcinoma , thyroid gland papillary carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 1/2
NCT01116648
Apr 2010 → Oct 2018 overdue
fallopian tube carcinoma , ovarian endometrioid adenocarcinoma , ovarian serous surface papillary adenocarcinoma , primary peritoneal serous adenocarcinoma +1
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1/2
NCT01064648
Mar 2010 → Jun 2018 overdue
malignant epithelioid mesothelioma , malignant pleural mesothelioma , sarcomatoid mesothelioma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 1/2
NCT00662506
Apr 2008 → Apr 2014
adult glioblastoma , giant cell glioblastoma , gliosarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2 54 trials
Phase 2
NCT04739800
Jun 2021 → Jan 2023 overdue
fallopian tube clear cell adenocarcinoma , fallopian tube endometrioid adenocarcinoma , fallopian tube mucinous adenocarcinoma , fallopian tube serous adenocarcinoma +9
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT04090567
Jul 2020 → Dec 2027 expected
BRCA1-related cancer predisposition , BRCA2-related cancer predisposition , Her2-receptor negative breast cancer
M.D. Anderson Cancer Center
Recruiting
No outcome recorded
Phase 2
NCT03741426
Jul 2020 → Nov 2025
renal cell carcinoma
CCTU- Cancer Theme
Unknown
No outcome recorded
Phase 2
NCT04184518
May 2020 → Dec 2021
metastatic malignant neoplasm , uveal melanoma
Spanish Melanoma Group
Withdrawn
No outcome recorded
Phase 2
NCT03851614
Apr 2019 → Jan 2027 expected
colorectal cancer , leiomyosarcoma , pancreatic adenocarcinoma
University Health Network, Toronto
Active not recruiting
No outcome recorded
Phase 2
NCT03699449
Nov 2018 → Sep 2022
—
Yonsei University
Unknown
No outcome recorded
Phase 2
NCT03660826
Sep 2018 → Dec 2024 overdue
endometrial endometrioid adenocarcinoma , endometrial mixed adenocarcinoma , endometrial serous adenocarcinoma , endometrial undifferentiated carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03570437
May 2018 → Jan 2023
carcinosarcoma , endometrial cancer
University of Manchester
Unknown
No outcome recorded
Phase 2
NCT07648745
May 2018 → Jan 2025
fallopian tube carcinoma , intestinal obstruction , ovarian carcinoma , primary peritoneal carcinoma
Prof Gordon Jayson
Completed
No outcome recorded
Phase 2
NCT02899728
Mar 2018 → Mar 2020
small cell lung carcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT03334617
Dec 2017 → Sep 2024 overdue
non-small cell lung carcinoma
AstraZeneca
Active not recruiting
No outcome recorded
Phase 2
NCT02974621
Dec 2017 → Dec 2022 overdue
glioblastoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT02893917
Aug 2017 → Mar 2023 overdue
castration-resistant prostate carcinoma , metastatic prostate carcinoma , prostate adenocarcinoma , prostate neuroendocrine neoplasm
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT03314740
Jun 2017 → Apr 2021
ovarian neoplasm
Mario Negri Institute for Pharmacological Research
Completed
No outcome recorded
Phase 2
NCT03117933
Mar 2017 → Mar 2021
ovarian cancer
University of Oxford
Completed
No outcome recorded
Phase 2
NCT02889900
Jan 2017 → Aug 2019
—
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT02498613
Aug 2016 → Jun 2022 overdue
non-small cell lung carcinoma , pancreatic ductal adenocarcinoma , small cell lung carcinoma , triple-negative breast carcinoma
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT02345265
May 2016 → Jul 2022 overdue
fallopian tube endometrioid adenocarcinoma , fallopian tube serous adenocarcinoma , ovarian endometrioid adenocarcinoma , ovarian serous adenocarcinoma +1
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2
NCT02340611
Jun 2015 → Jun 2018
ovarian cancer
University Health Network, Toronto
Completed
No outcome recorded
Phase 2
NCT01391962
Jul 2011 → Nov 2023
alveolar soft part sarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01337401
Jul 2011 → Jul 2019
alveolar soft part sarcoma
Institute of Cancer Research, United Kingdom
Unknown
No outcome recorded
Phase 2
NCT01229111
Oct 2010 → Mar 2014
cholangiocarcinoma , gallbladder carcinoma , periampullary adenocarcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT01260688
Oct 2010 → Jan 2013
hormone-resistant prostate carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01132820
Jun 2010 → Jan 2016
endometrial adenosquamous carcinoma , endometrial clear cell adenocarcinoma , endometrial serous adenocarcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT01229930
Jun 2010 → Dec 2012
cervical cancer
University of Glasgow
Completed
No outcome recorded
Phase 2
NCT01062425
Feb 2010 → Dec 2015
adult glioblastoma , gliosarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00942877
Jul 2009 → Sep 2018
alveolar soft part sarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00427973
May 2009 → Apr 2010
adult hepatocellular carcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT00475150
May 2008 → Jul 2011
acute myeloid leukemia with 11q23 abnormalities , acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) , acute myeloid leukemia with t(8;21)(q22;q22) translocation , myelodysplastic syndrome
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00588900
Mar 2008 → May 2010
colorectal cancer
Alliance for Clinical Trials in Oncology
Terminated
No outcome recorded
Phase 2
NCT00527124
Nov 2007 → Jul 2012
prostate adenocarcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT00326599
Jun 2007 → Apr 2009
lung cancer
Alliance for Clinical Trials in Oncology
Completed
No outcome recorded
Phase 2
NCT00454805
Mar 2007 → Dec 2008
breast cancer
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00458978
Feb 2007 → May 2013
hypopharynx squamous cell carcinoma , larynx verrucous carcinoma , major salivary gland carcinoma , metastatic squamous cell carcinoma +6
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00423332
Jan 2007 → Mar 2008
renal cell carcinoma
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00436956
Oct 2006 → Feb 2010
prostate cancer
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00410904
Oct 2006 → Jul 2013
non-small cell lung carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00385203
Sep 2006 → Jun 2008
gastrointestinal stromal tumor , soft tissue sarcoma
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00306891
Jun 2006 → Jan 2008
cancer
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00321724
May 2006 → May 2007
B-cell chronic lymphocytic leukemia
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00326872
May 2006 → Aug 2011
neurofibroma of spinal cord , neurofibromatosis type 1 , plexiform neurofibroma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT00278343
Apr 2006 → Jun 2010
fallopian tube cancer , malignant epithelial tumor of ovary , primary peritoneal carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00303862
Mar 2006 → Mar 2011
clear cell renal carcinoma
National Cancer Institute (NCI)
Terminated
No outcome recorded
Phase 2
NCT00245063
Mar 2006 → Mar 2010
small cell lung carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00243061
Jan 2006 → Mar 2012
acral lentiginous melanoma , iris melanoma , lentigo maligna melanoma , medium/large size posterior uveal melanoma +3
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00278889
Jan 2006 → Nov 2007
colorectal cancer
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00305656
Jan 2006 → Apr 2012
adult glioblastoma , giant cell glioblastoma , gliosarcoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00227760
Dec 2005 → May 2013
renal cell carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00238394
Dec 2005 → Mar 2007
adult hepatocellular carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00309946
Dec 2005 → Sep 2010
malignant epithelioid mesothelioma , sarcomatoid mesothelioma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00264004
Nov 2005 → Jan 2007
neoplasm
AstraZeneca
Completed
No outcome recorded
Phase 2
NCT00243074
Nov 2005 → Apr 2010
sarcomatoid mesothelioma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00275028
Oct 2005 → Mar 2010
fallopian tube cancer , malignant epithelial tumor of ovary , primary peritoneal serous adenocarcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Phase 2
NCT00244881
Sep 2005 → Aug 2007
male breast carcinoma
National Cancer Institute (NCI)
Completed
No outcome recorded
Show 44 more trials
Phase 2/3 4 trials
Phase 2/3
NCT02502266
May 2016 → Jun 2023 overdue
fallopian tube clear cell adenocarcinoma , fallopian tube endometrioid adenocarcinoma , fallopian tube serous adenocarcinoma , fallopian tube transitional cell carcinoma +7
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 2/3
NCT00939848
Apr 2011 → Sep 2012
biliary tract neoplasm
University College, London
Completed
No outcome recorded
Phase 2/3
NCT00384176
Aug 2006 → Nov 2009
colorectal cancer
AstraZeneca
Completed
No outcome recorded
Phase 2/3
NCT00245154
Nov 2005 → Jul 2008
lung cancer
NCIC Clinical Trials Group
Completed
No outcome recorded
Phase 3 5 trials
Phase 3
NCT03278717
Jun 2018 → Dec 2023
ovarian cancer
University College, London
Unknown
No outcome recorded
Phase 3
NCT02446600
Mar 2016 → Feb 2020 overdue
fallopian tube clear cell adenocarcinoma , fallopian tube transitional cell carcinoma , ovarian clear cell adenocarcinoma , ovarian endometrioid adenocarcinoma +5
National Cancer Institute (NCI)
Active not recruiting
No outcome recorded
Phase 3
NCT00795340
Feb 2009 → Jan 2012
lung cancer
NCIC Clinical Trials Group
Completed
No outcome recorded
Phase 3
NCT00777153
Oct 2008 → Apr 2010
glioblastoma
AstraZeneca
Completed
No outcome recorded
Phase 3
NCT00399035
Nov 2006 → Mar 2010
colorectal cancer
AstraZeneca
Completed
No outcome recorded
Phase not applicable 2 trials
—
NCT02681237
Apr 2016 → Jan 2022
ovarian cancer
University Health Network, Toronto
Completed
No outcome recorded
—
NCT00310089
Jan 2006 → Jul 2007
breast cancer
National Cancer Institute (NCI)
Completed
No outcome recorded