drugset / Trial / NCT00960349

Study of Cediranib Plus Cisplatin Plus Capecitabine/S-1 in Japanese Gastric Cancer Patients

NCT00960349

Phase 1 Completed 14 enrolled AstraZeneca
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary objective of the study is to assess the safety and tolerability of cediranib in combination with Cisplatin plus a Fluoropyrimidine (Capecitabine or S-1) in Japanese patients with previously untreated locally advanced or metastatic unresectable gastric cancer (GC).

Timeline

Start
2009-08
Primary completion
2010-01
Completion
2011-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Subject Cediranib Small molecule 20 mg Oral
Subject Cisplatin Other / unclassified 60 mg/m2 Intravenous
Subject Cisplatin Other / unclassified 80 mg/m2 Intravenous
Subject S-1 Small molecule 80 mg Oral
Subject S-1 Small molecule 120 mg Oral

Indications