drugset / Trial / NCT00757822
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
Timeline
- Start
- 2009-12
- Primary completion
- 2013-12
- Completion
- 2015-04
Outcome
Missed primary endpoint
registry analysis (superiority or other test); Arm 1:Dronabinol vs Arm 2:Ondansetron; p >0.76; Difference in Percentages 4.6 (90% CI -9.5 to 18.6); Fisher Exact NCT00757822 ↗
registry analysis (superiority or other test); Arm 1: Dronabinol vs Arm 2:Ondansetron; p >0.92; Fisher Exact NCT00757822 ↗
registry analysis (superiority or other test); Arm 1: Dronabinol vs Arm 2:Ondansetron; p >0.55; Difference in Percentages 7.7 (90% CI -12.1 to 13.3); Fisher Exact NCT00757822 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dronabinol | Other / unclassified | 5 mg | Oral |
| Comparator | Ondansetron | Other / unclassified | 4 mg | Intravenous |
Indications
No indication recorded.