Phenylephrine Pediatric Pharmacokinetic Study

Phase 1 Completed 36 enrolled Johnson & Johnson Consumer and Personal Products Worldwide

Non-randomizedSingle-groupOpen-labelBasic science

Summary

To characterize the pharmacokinetics of phenylephrine in two pediatric populations: children, ages 2 to \<12 years, and adolescents, ages 12 to \<18 years.

Timeline

Start: 2008-09
Primary completion: 2008-11
Completion: 2008-11

Publications

Gelotte CK, Parasrampuria DA, Zimmerman BA. Single-Dose Pharmacokinetics and Metabolism of the Oral Decongestant Phenylephrine HCl in Children and Adolescents. Pulm Ther. 2023 Mar;9(1):139-150. doi: 10.1007/s41030-022-00206-8. Epub 2022 Dec 8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Phenylephrine	Small molecule	2.5 mg	Oral
Subject	Phenylephrine	Small molecule	10 mg	Oral

Phenylephrine Pediatric Pharmacokinetic Study

Summary

Timeline

Publications

Drugs

Indications