drugset / Trial / NCT00766220
Yttrium Microspheres With Cetuximab Plus Irinotecan for Patients With Advanced Colorectal Cancer Mets to Liver
RandomizedSingle-groupSingle-blindTreatment
Summary
The goal of this clinical research study is to find out what effects radioactive particles, SIR-spheres, have when injected into the liver, followed by systemic chemotherapy with a combination of cetuximab and irinotecan compared to those who have systemic therapy alone, in patients with colon cancer that has metastasized to the liver. The safety of this treatment and how well it controls the disease will also be studied.
Timeline
- Start
- 2009-10
- Primary completion
- 2012-01
- Completion
- 2012-01
Outcome
Outcome not reported
Stopped (Enrollment): “Slow Accrual and withdrawn/exclusion of 2 participants.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cetuximab | Monoclonal antibody | 250 mg/m2 | Intravenous |
| Comparator | Irinotecan | Small molecule | 300 mg/m2 | Intravenous |
| Comparator | Irinotecan | Small molecule | 350 mg/m2 | Intravenous |
| Comparator | SIR-Spheres | Other / unclassified | — | Other |