drugset / Trial / NCT00766220

Yttrium Microspheres With Cetuximab Plus Irinotecan for Patients With Advanced Colorectal Cancer Mets to Liver

NCT00766220 ↗

RandomizedSingle-groupSingle-blindTreatment

Summary

The goal of this clinical research study is to find out what effects radioactive particles, SIR-spheres, have when injected into the liver, followed by systemic chemotherapy with a combination of cetuximab and irinotecan compared to those who have systemic therapy alone, in patients with colon cancer that has metastasized to the liver. The safety of this treatment and how well it controls the disease will also be studied.

Timeline

Start
2009-10
Primary completion
2012-01
Completion
2012-01

Outcome

Outcome not reported

Stopped (Enrollment): “Slow Accrual and withdrawn/exclusion of 2 participants.”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cetuximab Monoclonal antibody 250 mg/m2 Intravenous
Comparator Irinotecan Small molecule 300 mg/m2 Intravenous
Comparator Irinotecan Small molecule 350 mg/m2 Intravenous
Comparator SIR-Spheres Other / unclassified — Other

Indications