drugset / Trial / NCT00769613

Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections

NCT00769613

Open-labelSupportive care

Summary

RATIONALE: White blood cells that have been treated in the laboratory may kill cells that are infected with cytomegalovirus. PURPOSE: This phase I trial is studying how well cytotoxic T cells work in treating patients who have undergone donor stem cell transplant and have cytomegalovirus infections.

Timeline

Start
2008-08
Primary completion
2014-08
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject cytomegalovirus IE-1-specific cytotoxic T lymphocytes Cell therapy
Subject cytomegalovirus pp65-specific cytotoxic T lymphocytes Cell therapy
Subject therapeutic allogeneic lymphocytes Cell therapy

Indications