drugset / Trial / NCT00770367

Pioglitazone and Serum Asymmetric Dimethylarginine (ADMA) in Patients With Diabetes

NCT00770367

RandomizedCrossoverQuadruple-blindPrevention

Summary

SPECIFIC AIMS 1. To determine whether pioglitazone will reduce levels of asymmetric dimethylarginine(ADMA) in patients with diabetes. 2. To determine whether nitric oxide(NOx) products are increased with pioglitazone treatment. 3. To determine whether pioglitazone reduces oxidative stress (F2-isoprostanes).

Timeline

Start
2008-10
Primary completion
2009-12
Completion
2010-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Pioglitazone Small molecule 30 mg

Indications