drugset / Trial / NCT00772031
NINDS CRC Chronic Migraine Treatment Trial
Phase 3
Completed
191 enrolled
Anne Lindblad
National Institute of Neurological Disorders and Stroke (NINDS) · collabOrtho-McNeil Janssen Scientific Affairs, LLC · collab
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The purpose of this study is to compare the reduction in the number of severe headache days at six months in people with chronic migraine treated with topiramate and propranolol versus those treated with topiramate and a placebo.
Timeline
- Start
- 2008-10
- Primary completion
- 2010-09
- Completion
- 2010-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propranolol | Small molecule | 240 mg | — |
| Comparator | Topiramate | Small molecule | — | — |