drugset / Trial / NCT00774527
Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT
RandomizedParallel-groupOpen-labelTreatment
Summary
Randomized comparison of cyclophosphamide versus reduced-dose cyclophosphamide plus fludarabine in addition to anti-thymocyte globulin for the conditioning therapy in allogeneic hematopoietic cell transplantation for bone marrow failure syndrome.
Timeline
- Start
- 2003-03
- Primary completion
- 2010-02
- Completion
- 2011-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cyclophosphamide | Other / unclassified | 50 mg/kg | Intravenous |
| Comparator | Fludarabine | Small molecule | 30 mg/m2 | Intravenous |
| Comparator | Lymphoglobuline | Unknown | 15 mg/kg | Intravenous |
| Comparator | Thymoglobulin | Protein / enzyme biologic | 3 mg/kg | Intravenous |